The Distribution of Dioxin Concentrations in the Blood of Yusho Patients

Jumboku Kajiwara, Takashi Todaka, Hironori Hirakawa, Tsuguhide Hori, Teruaki Hirata, Takao Iida, Hiroshi Uchi, Masutaka Furue

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

抄録

In 1968, the contamination of cooking oil by heat-degraded polychlorinated biphenyls (PCBs) caused a case of mass poisoning, the so-called Yusho incident. The cause of Yusho disease is thought to be ingested toxic substances, including not only PCBs but also polychlorinated dibenzofuran (PCDFs) in Kanemi rice oil. We previously measured dioxins concentrations in the blood of 854 Yusho patients by annual medical examination from 2001 to 2013. We determined the concentrations of 2,3,4,7,8-PeCDF, 1,2,3,4,7,8-HxCDF, 1,2,3,6,7,8-HxCDF and 3,3',4,4',5,5'-HxCB (#169) in the blood of Yusho patients were more than double those of normal controls. In 2012, a new Yusho criteria was established. Family members living with a Yusho patient were also certified as Yusho patients and called Yusho family cohabitant patients. In this study, we compared the distribution of 2,3,4,7,8-PeCDF concentration in the blood of Yusho patients and Yusho family cohabitant patients. It was suspected that the distribution of 2,3,4,7,8-PeCDF concentration in Yusho family cohabitant patients would be lower than that of Yusho patients.

元の言語英語
ページ(範囲)149-153
ページ数5
ジャーナルFukuoka igaku zasshi = Hukuoka acta medica
106
発行部数5
出版物ステータス出版済み - 5 1 2015

Fingerprint

Dioxins
Polychlorinated Biphenyls
Oils
Poisons
Cooking
Poisoning
Hot Temperature

All Science Journal Classification (ASJC) codes

  • Medicine(all)

これを引用

Kajiwara, J., Todaka, T., Hirakawa, H., Hori, T., Hirata, T., Iida, T., ... Furue, M. (2015). The Distribution of Dioxin Concentrations in the Blood of Yusho Patients. Fukuoka igaku zasshi = Hukuoka acta medica, 106(5), 149-153.

The Distribution of Dioxin Concentrations in the Blood of Yusho Patients. / Kajiwara, Jumboku; Todaka, Takashi; Hirakawa, Hironori; Hori, Tsuguhide; Hirata, Teruaki; Iida, Takao; Uchi, Hiroshi; Furue, Masutaka.

:: Fukuoka igaku zasshi = Hukuoka acta medica, 巻 106, 番号 5, 01.05.2015, p. 149-153.

研究成果: ジャーナルへの寄稿記事

Kajiwara, J, Todaka, T, Hirakawa, H, Hori, T, Hirata, T, Iida, T, Uchi, H & Furue, M 2015, 'The Distribution of Dioxin Concentrations in the Blood of Yusho Patients', Fukuoka igaku zasshi = Hukuoka acta medica, 巻. 106, 番号 5, pp. 149-153.
Kajiwara J, Todaka T, Hirakawa H, Hori T, Hirata T, Iida T その他. The Distribution of Dioxin Concentrations in the Blood of Yusho Patients. Fukuoka igaku zasshi = Hukuoka acta medica. 2015 5 1;106(5):149-153.
Kajiwara, Jumboku ; Todaka, Takashi ; Hirakawa, Hironori ; Hori, Tsuguhide ; Hirata, Teruaki ; Iida, Takao ; Uchi, Hiroshi ; Furue, Masutaka. / The Distribution of Dioxin Concentrations in the Blood of Yusho Patients. :: Fukuoka igaku zasshi = Hukuoka acta medica. 2015 ; 巻 106, 番号 5. pp. 149-153.
@article{a6112b7c548e4bf6958f48d48764efd2,
title = "The Distribution of Dioxin Concentrations in the Blood of Yusho Patients",
abstract = "In 1968, the contamination of cooking oil by heat-degraded polychlorinated biphenyls (PCBs) caused a case of mass poisoning, the so-called Yusho incident. The cause of Yusho disease is thought to be ingested toxic substances, including not only PCBs but also polychlorinated dibenzofuran (PCDFs) in Kanemi rice oil. We previously measured dioxins concentrations in the blood of 854 Yusho patients by annual medical examination from 2001 to 2013. We determined the concentrations of 2,3,4,7,8-PeCDF, 1,2,3,4,7,8-HxCDF, 1,2,3,6,7,8-HxCDF and 3,3',4,4',5,5'-HxCB (#169) in the blood of Yusho patients were more than double those of normal controls. In 2012, a new Yusho criteria was established. Family members living with a Yusho patient were also certified as Yusho patients and called Yusho family cohabitant patients. In this study, we compared the distribution of 2,3,4,7,8-PeCDF concentration in the blood of Yusho patients and Yusho family cohabitant patients. It was suspected that the distribution of 2,3,4,7,8-PeCDF concentration in Yusho family cohabitant patients would be lower than that of Yusho patients.",
author = "Jumboku Kajiwara and Takashi Todaka and Hironori Hirakawa and Tsuguhide Hori and Teruaki Hirata and Takao Iida and Hiroshi Uchi and Masutaka Furue",
year = "2015",
month = "5",
day = "1",
language = "English",
volume = "106",
pages = "149--153",
journal = "Fukuoka Acta Medica",
issn = "0016-254X",
publisher = "福岡医学会",
number = "5",

}

TY - JOUR

T1 - The Distribution of Dioxin Concentrations in the Blood of Yusho Patients

AU - Kajiwara, Jumboku

AU - Todaka, Takashi

AU - Hirakawa, Hironori

AU - Hori, Tsuguhide

AU - Hirata, Teruaki

AU - Iida, Takao

AU - Uchi, Hiroshi

AU - Furue, Masutaka

PY - 2015/5/1

Y1 - 2015/5/1

N2 - In 1968, the contamination of cooking oil by heat-degraded polychlorinated biphenyls (PCBs) caused a case of mass poisoning, the so-called Yusho incident. The cause of Yusho disease is thought to be ingested toxic substances, including not only PCBs but also polychlorinated dibenzofuran (PCDFs) in Kanemi rice oil. We previously measured dioxins concentrations in the blood of 854 Yusho patients by annual medical examination from 2001 to 2013. We determined the concentrations of 2,3,4,7,8-PeCDF, 1,2,3,4,7,8-HxCDF, 1,2,3,6,7,8-HxCDF and 3,3',4,4',5,5'-HxCB (#169) in the blood of Yusho patients were more than double those of normal controls. In 2012, a new Yusho criteria was established. Family members living with a Yusho patient were also certified as Yusho patients and called Yusho family cohabitant patients. In this study, we compared the distribution of 2,3,4,7,8-PeCDF concentration in the blood of Yusho patients and Yusho family cohabitant patients. It was suspected that the distribution of 2,3,4,7,8-PeCDF concentration in Yusho family cohabitant patients would be lower than that of Yusho patients.

AB - In 1968, the contamination of cooking oil by heat-degraded polychlorinated biphenyls (PCBs) caused a case of mass poisoning, the so-called Yusho incident. The cause of Yusho disease is thought to be ingested toxic substances, including not only PCBs but also polychlorinated dibenzofuran (PCDFs) in Kanemi rice oil. We previously measured dioxins concentrations in the blood of 854 Yusho patients by annual medical examination from 2001 to 2013. We determined the concentrations of 2,3,4,7,8-PeCDF, 1,2,3,4,7,8-HxCDF, 1,2,3,6,7,8-HxCDF and 3,3',4,4',5,5'-HxCB (#169) in the blood of Yusho patients were more than double those of normal controls. In 2012, a new Yusho criteria was established. Family members living with a Yusho patient were also certified as Yusho patients and called Yusho family cohabitant patients. In this study, we compared the distribution of 2,3,4,7,8-PeCDF concentration in the blood of Yusho patients and Yusho family cohabitant patients. It was suspected that the distribution of 2,3,4,7,8-PeCDF concentration in Yusho family cohabitant patients would be lower than that of Yusho patients.

UR - http://www.scopus.com/inward/record.url?scp=84940973350&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84940973350&partnerID=8YFLogxK

M3 - Article

C2 - 26226677

AN - SCOPUS:84940973350

VL - 106

SP - 149

EP - 153

JO - Fukuoka Acta Medica

JF - Fukuoka Acta Medica

SN - 0016-254X

IS - 5

ER -