抄録
Besides having an inhibitory effect of chemical mediator release from mast cells, IPD has an inhibitory effect of Th2 cytokines (IgE production by IL-4 inhibition and eosinophil proliferation by IL-5 inhibition). We administered IPD to patients with atopic dermatitis and evaluated the blood levels of IgE and eosinophil counts. IPD significantly improved the severity of the skin, but did not influence the IgE production and eosinophil number. However, IPD potentiy decreased the levels of IgE in 2 patients with marked hyperimmunoglobulinemia E. These results suggest that IPD is markedly useful in a certain group of patients with atopic dermatitis.
| 元の言語 | 英語 |
|---|---|
| ページ（範囲） | 38-44 |
| ページ数 | 7 |
| ジャーナル | Skin Research |
| 巻 | 6 |
| 発行部数 | SUPPL. 8 |
| 出版物ステータス | 出版済み - 3 1 2007 |
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All Science Journal Classification (ASJC) codes
- Dermatology
- Infectious Diseases
これを引用
The effect of IPD in atopic dermatitis. / Fukagawa, Shuji; Furue, Masutaka.
：: Skin Research, 巻 6, 番号 SUPPL. 8, 01.03.2007, p. 38-44.研究成果: ジャーナルへの寄稿 › 記事
}
TY - JOUR
T1 - The effect of IPD in atopic dermatitis
AU - Fukagawa, Shuji
AU - Furue, Masutaka
PY - 2007/3/1
Y1 - 2007/3/1
N2 - Besides having an inhibitory effect of chemical mediator release from mast cells, IPD has an inhibitory effect of Th2 cytokines (IgE production by IL-4 inhibition and eosinophil proliferation by IL-5 inhibition). We administered IPD to patients with atopic dermatitis and evaluated the blood levels of IgE and eosinophil counts. IPD significantly improved the severity of the skin, but did not influence the IgE production and eosinophil number. However, IPD potentiy decreased the levels of IgE in 2 patients with marked hyperimmunoglobulinemia E. These results suggest that IPD is markedly useful in a certain group of patients with atopic dermatitis.
AB - Besides having an inhibitory effect of chemical mediator release from mast cells, IPD has an inhibitory effect of Th2 cytokines (IgE production by IL-4 inhibition and eosinophil proliferation by IL-5 inhibition). We administered IPD to patients with atopic dermatitis and evaluated the blood levels of IgE and eosinophil counts. IPD significantly improved the severity of the skin, but did not influence the IgE production and eosinophil number. However, IPD potentiy decreased the levels of IgE in 2 patients with marked hyperimmunoglobulinemia E. These results suggest that IPD is markedly useful in a certain group of patients with atopic dermatitis.
UR - http://www.scopus.com/inward/record.url?scp=34249062696&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34249062696&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:34249062696
VL - 6
SP - 38
EP - 44
JO - Skin Research
JF - Skin Research
SN - 0018-1390
IS - SUPPL. 8
ER -