The effect of IPD in atopic dermatitis

Shuji Fukagawa, Masutaka Furue

研究成果: ジャーナルへの寄稿記事


Besides having an inhibitory effect of chemical mediator release from mast cells, IPD has an inhibitory effect of Th2 cytokines (IgE production by IL-4 inhibition and eosinophil proliferation by IL-5 inhibition). We administered IPD to patients with atopic dermatitis and evaluated the blood levels of IgE and eosinophil counts. IPD significantly improved the severity of the skin, but did not influence the IgE production and eosinophil number. However, IPD potentiy decreased the levels of IgE in 2 patients with marked hyperimmunoglobulinemia E. These results suggest that IPD is markedly useful in a certain group of patients with atopic dermatitis.

ジャーナルSkin Research
発行部数SUPPL. 8
出版物ステータス出版済み - 3 1 2007


All Science Journal Classification (ASJC) codes

  • Dermatology
  • Infectious Diseases


Fukagawa, S., & Furue, M. (2007). The effect of IPD in atopic dermatitis. Skin Research, 6(SUPPL. 8), 38-44.