TY - JOUR
T1 - The effect of traditional Tibetan guozhuang dance on vascular health in elderly individuals living at high altitudes
AU - Li, Guofeng
AU - Zhu, Aiqin
AU - Huang, Yuling
AU - Meng, Jie
AU - Ji, Lei
AU - Xue, Jinsheng
AU - Li, Hongjuan
AU - Wang, Xiaohong
AU - Luo, Junming
AU - Wu, Zhou
AU - Wu, Shizheng
N1 - Funding Information:
The authors would like to thank Dr. David Wang and Rujun Gong for critically reviewing the manuscript. The authors would also like to thank the Centre Laboratory of Qinghai Provincial People’s Hospital for their helpful comments and feedback throughout this study and the Qinghai Sport Bureau for supporting and enrolling the study participants. The study was supported in part by a Key Grant for Returnees on Science and Technology from the Ministry of
Funding Information:
The authors would like to thank Dr. David Wang and Rujun Gong for critically reviewing the manuscript. The authors would also like to thank the Centre Laboratory of Qinghai Provincial People?s Hospital for their helpful comments and feedback throughout this study and the Qinghai Sport Bureau for supporting and enrolling the study participants. The study was supported in part by a Key Grant for Returnees on Science and Technology from the Ministry of Personnel, China (NO: 2014-414), The National Natural Science Foundation of China (NO: 201608635002), Qinghai Province Application of Basic Research Projects (NO: 2013-Z-768), and the State Scholarship Fund of China scholarship council (NO: 201608635002) to Aiqin Zhu.
Publisher Copyright:
© 2020 E-Century Publishing Corporation. All rights reserved.
PY - 2020
Y1 - 2020
N2 - To evaluate the effect of dance on vascular-related factors and cerebral hemodynamics in elderly individuals in Qinghai-Tibetan plateau regions (mean altitude ≥2,300 m). Thirty elderly individuals, who practiced traditional Tibetan Guozhuang dance or did not, were enrolled, respectively. Serum PGC-1α, HCY, FSTL-1, VEGF and HIF-1α were measured by ELISA assays. Carotid artery stenosis and plaque, IMT, extracranial internal carotid artery stenosis and cerebral arteriosclerosis were evaluated using CUS and TCD. Body weight, BMI, heart rate, systolic pressure, and diastolic pressure, serum BGS, TC, LDL, HIF-1α, VEGF, and HCY in the dance group were significantly lower than the no-dance group. FSTL-1 levels, SO2 and SO2/heart rate ratio in the dance group were significantly higher than the no-dance group. Incidence of extracranial internal carotid artery stenosis, carotid stenosis and plaque in the dance group was significantly lower than the no-dance group. IMT was a significant positive correlation between PGC-1α and HCY in the no-dance group. Elderly individuals who regularly practiced Tibetan dance had improved blood vessel functionality and cerebral hemodynamic at high altitudes.
AB - To evaluate the effect of dance on vascular-related factors and cerebral hemodynamics in elderly individuals in Qinghai-Tibetan plateau regions (mean altitude ≥2,300 m). Thirty elderly individuals, who practiced traditional Tibetan Guozhuang dance or did not, were enrolled, respectively. Serum PGC-1α, HCY, FSTL-1, VEGF and HIF-1α were measured by ELISA assays. Carotid artery stenosis and plaque, IMT, extracranial internal carotid artery stenosis and cerebral arteriosclerosis were evaluated using CUS and TCD. Body weight, BMI, heart rate, systolic pressure, and diastolic pressure, serum BGS, TC, LDL, HIF-1α, VEGF, and HCY in the dance group were significantly lower than the no-dance group. FSTL-1 levels, SO2 and SO2/heart rate ratio in the dance group were significantly higher than the no-dance group. Incidence of extracranial internal carotid artery stenosis, carotid stenosis and plaque in the dance group was significantly lower than the no-dance group. IMT was a significant positive correlation between PGC-1α and HCY in the no-dance group. Elderly individuals who regularly practiced Tibetan dance had improved blood vessel functionality and cerebral hemodynamic at high altitudes.
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M3 - Article
AN - SCOPUS:85090481246
SN - 1943-8141
VL - 12
SP - 4550
EP - 4560
JO - American Journal of Translational Research
JF - American Journal of Translational Research
IS - 8
ER -
