The gacA gene of Pseudomonas aeruginosa PAO1 is not required for full virulence in Bombyx mori

研究成果: ジャーナルへの寄稿記事

4 引用 (Scopus)

抄録

It is known that the GacS/GacA two-component system is important for the virulence of Pseudomonas aeruginosa in invertebrate and vertebrate hosts and in plants (Rahme et al., 1995; Tan et al., 1999; Jander et al., 2000). In this study, the gacA nonpolar mutant C2 and polar mutant C3 were generated and inoculated into Bombyx mori. The polar mutants showed reduced virulence, whereas no significant difference was observed between the gacA nonpolar mutant and wild type strain with respect to the ability to kill B. mori larvae. This suggests that the reduced virulence was due to a polar effect of the insertions, rather than to the lack of the gacA gene product.

元の言語英語
ページ(範囲)89-95
ページ数7
ジャーナルJournal of Insect Biotechnology and Sericology
76
発行部数2
出版物ステータス出版済み - 6 1 2007

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Bombyx
Bombyx mori
Pseudomonas aeruginosa
Virulence
virulence
Genes
mutants
genes
Invertebrates
Larva
Vertebrates
invertebrates
vertebrates
Gene
larvae

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Applied Microbiology and Biotechnology
  • Business, Management and Accounting(all)
  • Agricultural and Biological Sciences(all)
  • Insect Science
  • Industrial and Manufacturing Engineering

これを引用

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title = "The gacA gene of Pseudomonas aeruginosa PAO1 is not required for full virulence in Bombyx mori",
abstract = "It is known that the GacS/GacA two-component system is important for the virulence of Pseudomonas aeruginosa in invertebrate and vertebrate hosts and in plants (Rahme et al., 1995; Tan et al., 1999; Jander et al., 2000). In this study, the gacA nonpolar mutant C2 and polar mutant C3 were generated and inoculated into Bombyx mori. The polar mutants showed reduced virulence, whereas no significant difference was observed between the gacA nonpolar mutant and wild type strain with respect to the ability to kill B. mori larvae. This suggests that the reduced virulence was due to a polar effect of the insertions, rather than to the lack of the gacA gene product.",
author = "Yuuka Chieda and Kazuhiro Iiyama and Lee, {Jae Man} and Takahiro Kusakabe and Chisa Yasunaga-Aoki and Susumu Shimizu",
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T1 - The gacA gene of Pseudomonas aeruginosa PAO1 is not required for full virulence in Bombyx mori

AU - Chieda, Yuuka

AU - Iiyama, Kazuhiro

AU - Lee, Jae Man

AU - Kusakabe, Takahiro

AU - Yasunaga-Aoki, Chisa

AU - Shimizu, Susumu

PY - 2007/6/1

Y1 - 2007/6/1

N2 - It is known that the GacS/GacA two-component system is important for the virulence of Pseudomonas aeruginosa in invertebrate and vertebrate hosts and in plants (Rahme et al., 1995; Tan et al., 1999; Jander et al., 2000). In this study, the gacA nonpolar mutant C2 and polar mutant C3 were generated and inoculated into Bombyx mori. The polar mutants showed reduced virulence, whereas no significant difference was observed between the gacA nonpolar mutant and wild type strain with respect to the ability to kill B. mori larvae. This suggests that the reduced virulence was due to a polar effect of the insertions, rather than to the lack of the gacA gene product.

AB - It is known that the GacS/GacA two-component system is important for the virulence of Pseudomonas aeruginosa in invertebrate and vertebrate hosts and in plants (Rahme et al., 1995; Tan et al., 1999; Jander et al., 2000). In this study, the gacA nonpolar mutant C2 and polar mutant C3 were generated and inoculated into Bombyx mori. The polar mutants showed reduced virulence, whereas no significant difference was observed between the gacA nonpolar mutant and wild type strain with respect to the ability to kill B. mori larvae. This suggests that the reduced virulence was due to a polar effect of the insertions, rather than to the lack of the gacA gene product.

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