The inhibitory effect on aldose reductase by an extract of Ganoderma lucidum

Sri Fatmawati, Kenji Kurashiki, Sayaka Takeno, Yong Ung Kim, Kuniyoshi Shimizu, Masao Sato, Katsumi Imaizumi, Kaori Takahashi, Shinji Kamiya, Shuhei Kaneko, Ryuichiro Kondo

研究成果: Contribution to journalArticle査読

31 被引用数 (Scopus)

抄録

The human aldose reductase inhibitory effects of the methanol extracts of 17 medicinal and edible mushrooms were examined. Ganoderma lucidum showed the highest aldose reductase inhibitory activity compared with the other mushrooms. The effect of an ethanol extract of G. lucidum on the galactitol level in the eye lens was studied in a galactosemic rat model in vivo. This mushroom significantly decreased the galactitol accumulation.

本文言語英語
ページ(範囲)28-32
ページ数5
ジャーナルPhytotherapy Research
23
1
DOI
出版ステータス出版済み - 1 1 2009

All Science Journal Classification (ASJC) codes

  • 薬理学

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