The inhibitory effects of mushroom extracts on sucrose-dependent oral biofilm formation

Akira Yano, Sayaka Kikuchi, Yoshihisa Yamashita, Yuichi Sakamoto, Yuko Nakagawa, Yasuo Yoshida

研究成果: ジャーナルへの寄稿学術誌査読

16 被引用数 (Scopus)

抄録

Mushrooms contain large quantities of α-glucans. Shiitake (Lentinula edodes), Japan's most popular edible mushroom, has been reported to contain about 6% (weight/dried weight) of α-(1,3)-glucan. This glucan is one of the major components of oral biofilm formed by the cariogenic bacteria Streptococcus mutans and Streptococcus sobrinus. We found that extracts from shiitake and other edible mushrooms could reduce preformed biofilms of S. mutans and S. sobrinus in the presence of dextranase. We also investigated the α-glucanase activities of shiitake mushroom extracts and their effects on biofilm formation. The extracts possessed α-glucanase activity and degraded water-insoluble glucans from mutans streptococci. The extracts strongly inhibited the sucrose-dependent formation of biofilms by S. mutans and S. sobrinus in the presence of dextranase. Our results suggest that some components of mushrooms, including α-glucanases, might inhibit the sucrose-induced formation of oral biofilms.

本文言語英語
ページ(範囲)615-623
ページ数9
ジャーナルApplied Microbiology and Biotechnology
86
2
DOI
出版ステータス出版済み - 3月 2010

!!!All Science Journal Classification (ASJC) codes

  • バイオテクノロジー
  • 応用微生物学とバイオテクノロジー

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