The nucleoid protein H-NS facilitates chromosome DNA replication in Escherichia coli dnaA mutants

Tsutomu Katayama, Makoto Takata, Kazuhisa Sekimizu

研究成果: ジャーナルへの寄稿学術誌査読

22 被引用数 (Scopus)

抄録

Growth inhibition of the dnaA(Cs) mutant, which overinitiates chromosome replication, was shown to be dependent upon the nucleoid protein H-NS. [3H]thymine incorporation experiments indicated that the absence of H-NS inhibited overreplication by the dnaA(Cs) mutant. In addition, the temperature-sensitive phenotype of a dnaA46 mutant was enhanced by disruption of H-NS. These observations suggest that H-NS directly or indirectly facilitates the initiation of chromosome replication.

本文言語英語
ページ(範囲)5790-5792
ページ数3
ジャーナルJournal of bacteriology
178
19
DOI
出版ステータス出版済み - 1996

!!!All Science Journal Classification (ASJC) codes

  • 微生物学
  • 分子生物学

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