The pedipump: A versatile, implantable pediatric ventricular assist device - Update IV

Brian W. Duncan, Kiyotaka Fukamachi, Lawrence D. Noble, David T. Dudzinski, Christine R. Flick, Hideyuki Fumoto, Akira Shiose, Yoko Arakawa, Tohru Takaseya, Fernando Casas, William A. Smith

研究成果: Contribution to journalShort survey査読

7 被引用数 (Scopus)

抄録

Cleveland Clinic's PediPump (Cleveland, OH, USA) is a ventricular assist device designed for the support of pediatric patients. The PediPump is a mixed-flow ventricular assist device with a magnetically suspended impeller measuring 10.5 mm in diameter by 64.5 mm in length. Progress and achievements for the PediPump program are considered according to the development project's three primary objectives: Basic engineering: along with size reductions, substantial design improvements have been incorporated in each design iteration including the motor, magnetic bearings, axial touch points, and heat transfer path; Anatomic modeling and device fitting studies: Techniques based on computed tomography and magnetic resonance imaging have been developed to create three-dimensional anatomic-modeling and device-fitting tools to facilitate device implantation and to assist in preoperative planning. For in vivo testing, to date, six acute (6-h duration) and nine chronic (30-day target duration) implantations have been performed in sheep; the implantation of the PediPump appears to be relatively easy with excellent hemodynamic performance and minimal hemolysis during support. Cleveland Clinic's PediPump program supported by the National Heart, Lung and Blood Institute's Pediatric Circulatory Support Program has led to the development of a pediatric ventricular assist device that has satisfactory performance in preclinical evaluation and appears to be ready to support a program of clinical testing.

本文言語英語
ページ(範囲)1005-1008
ページ数4
ジャーナルArtificial Organs
33
11
DOI
出版ステータス出版済み - 11 1 2009
外部発表はい

All Science Journal Classification (ASJC) codes

  • バイオエンジニアリング
  • 医学(その他)
  • 生体材料
  • 生体医工学

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