The relationship between three signs of fetal magnetic resonance imaging and severity of congenital diaphragmatic hernia

T. Hattori, M. Hayakawa, M. Ito, Y. Sato, K. Tamakoshi, Y. Kanamori, H. Okuyama, N. Inamura, S. Takahashi, Y. Fujino, T. Taguchi, N. Usui

研究成果: Contribution to journalArticle査読

5 被引用数 (Scopus)

抄録

Objective:To seek a simple approach for prenatally classifying congenital diaphragmatic hernia (CDH) severity using fetal magnetic resonance imaging (MRI) markers.Study design:A retrospective, multicenter study using questionnaires to investigate fetal MRI findings. We included fetuses prenatally diagnosed with isolated left-sided CDH and delivered after 36 weeks of gestation. We focused on three fetal MRI morphological signs: incomplete pulmonary baseline (IPB), liver up (LU) and retrocardiac stomach (RCS). We also evaluated the fetal MRI score defined as the total number of positive signs; the primary outcome was survival at discharge.Results:In 256 patients (from 56 institutions), IPB, LU and RCS findings correlated with lower survival: odds ratio (95% confidence interval), 0.16 (0.08 to 0.33); 0.24 (0.12 to 0.51); and 0.14 (0.07 to 0.28); respectively. Patients with higher fetal MRI scores had a higher mortality rate.Conclusion:IPB, LU and RCS on fetal MRI are related to CDH severity.

本文言語英語
ページ(範囲)265-269
ページ数5
ジャーナルJournal of Perinatology
37
3
DOI
出版ステータス出版済み - 3 1 2017

All Science Journal Classification (ASJC) codes

  • 小児科学、周産期医学および子どもの健康
  • 産婦人科学

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