The specific, diverse effects of purine and pyrimidine nucleoside-5'-di(tri)-3'-diphosphates on the eucaryote translation system in vitro.

M. Furuichi, N. Hamada, O. Nakamura, A. Razzaque, J. I. Mukai, S. Murao, T. Nishino

研究成果: ジャーナルへの寄稿記事

抄録

All the eight 5'-di(tri)-3'-diphosphates of four common ribonucleosides were prepared by the enzymic pyrophosphoryl transfer catalysed by Streptomyces adephospholyticus ATP:nucleotide pyrophosphokinase (E.C.2.7.6.4) form dATP to the respective 5'-phosphates, and their effects on the translation of mRNAs by a wheat germ system in vitro were studied. (p) ppPupp decreased the total 14C-leucine incorporation directed by a rat liver mRNA whereas (p) ppPypp did not. With a silkworm pupa ovary mRNA, distinctly reverase results were obtained. Gel electrophoretic profiles of the translation products disclosed the mRNA species-specific stimulatory or inhibitory effects for each of the polyphosphates tested.

元の言語英語
ページ(範囲)s151-154
ジャーナルNucleic acids symposium series
発行部数6
出版物ステータス出版済み - 12 1 1979
外部発表Yes

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Pyrimidine Nucleosides
Purine Nucleosides
Diphosphates
nucleotide pyrophosphokinase
Messenger RNA
Ribonucleosides
Polyphosphates
Pupa
Bombyx
Streptomyces
Protein Biosynthesis
Leucine
Triticum
Ovary
Gels
Phosphates
Liver
In Vitro Techniques

All Science Journal Classification (ASJC) codes

  • Medicine(all)

これを引用

The specific, diverse effects of purine and pyrimidine nucleoside-5'-di(tri)-3'-diphosphates on the eucaryote translation system in vitro. / Furuichi, M.; Hamada, N.; Nakamura, O.; Razzaque, A.; Mukai, J. I.; Murao, S.; Nishino, T.

:: Nucleic acids symposium series, 番号 6, 01.12.1979, p. s151-154.

研究成果: ジャーナルへの寄稿記事

Furuichi, M. ; Hamada, N. ; Nakamura, O. ; Razzaque, A. ; Mukai, J. I. ; Murao, S. ; Nishino, T. / The specific, diverse effects of purine and pyrimidine nucleoside-5'-di(tri)-3'-diphosphates on the eucaryote translation system in vitro. :: Nucleic acids symposium series. 1979 ; 番号 6. pp. s151-154.
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abstract = "All the eight 5'-di(tri)-3'-diphosphates of four common ribonucleosides were prepared by the enzymic pyrophosphoryl transfer catalysed by Streptomyces adephospholyticus ATP:nucleotide pyrophosphokinase (E.C.2.7.6.4) form dATP to the respective 5'-phosphates, and their effects on the translation of mRNAs by a wheat germ system in vitro were studied. (p) ppPupp decreased the total 14C-leucine incorporation directed by a rat liver mRNA whereas (p) ppPypp did not. With a silkworm pupa ovary mRNA, distinctly reverase results were obtained. Gel electrophoretic profiles of the translation products disclosed the mRNA species-specific stimulatory or inhibitory effects for each of the polyphosphates tested.",
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AU - Nakamura, O.

AU - Razzaque, A.

AU - Mukai, J. I.

AU - Murao, S.

AU - Nishino, T.

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