The up-to-date review of epidemiological pancreatic neuroendocrine tumors in Japan

Tetsuhide Ito, Lingaku Lee, Masayuki Hijioka, Ken Kawabe, Masaki Kato, Kazuhiko Nakamura, Keijiro Ueda, Ohtsuka Takao, Hisato Igarashi

研究成果: ジャーナルへの寄稿記事

13 引用 (Scopus)

抄録

Pancreatic neuroendocrine tumors (PNETs) were considered an extremely rare disease. However, in recent years, the number of patients with PNET has increased rapidly. According to an epidemiological survey conducted in Japan, the number of treated patients with PNETs in 2010 was approximately 1.2-times that in 2005, and the number of new incidences of non-functional PNETs in 2010 was approximately 1.7-times that in 2005. Among functional PNETs, insulinoma was most prevalent, followed by gastrinoma. To diagnose PNETs, correct histological diagnosis is most important. According to the World Health Organization 2010 classification criteria, neuroendocrine tumors (NETs) are categorized into well-differentiated NETs and poorly differentiated neuroendocrine carcinomas (NECs). NECs accounted for 7.6% of all NETs, and functional and non-functional PNETs accounted for 2.1% and 10.1%, respectively. Patients with distant metastasis accounted for 19.9%, and those with multiple endocrine neoplasia type 1 accounted for 4.3%. When treating PNETs, it is necessary to correctly evaluate the functionality and progression of tumors, the presence or absence of metastasis, and the degrees of differentiation and malignant potential of tumors. A new registration system from the Japan Neuroendocrine Tumor Society will start to be used in 2015, which will help further dissemination of Japanese epidemiological information to the world.

元の言語英語
ページ(範囲)574-577
ページ数4
ジャーナルJournal of Hepato-Biliary-Pancreatic Sciences
22
発行部数8
DOI
出版物ステータス出版済み - 8 1 2015

Fingerprint

Neuroendocrine Tumors
Japan
Neuroendocrine Carcinoma
Gastrinoma
Neoplasm Metastasis
Multiple Endocrine Neoplasia Type 1
Insulinoma
Rare Diseases
Neoplasms

All Science Journal Classification (ASJC) codes

  • Surgery
  • Hepatology

これを引用

The up-to-date review of epidemiological pancreatic neuroendocrine tumors in Japan. / Ito, Tetsuhide; Lee, Lingaku; Hijioka, Masayuki; Kawabe, Ken; Kato, Masaki; Nakamura, Kazuhiko; Ueda, Keijiro; Takao, Ohtsuka; Igarashi, Hisato.

:: Journal of Hepato-Biliary-Pancreatic Sciences, 巻 22, 番号 8, 01.08.2015, p. 574-577.

研究成果: ジャーナルへの寄稿記事

Ito, Tetsuhide ; Lee, Lingaku ; Hijioka, Masayuki ; Kawabe, Ken ; Kato, Masaki ; Nakamura, Kazuhiko ; Ueda, Keijiro ; Takao, Ohtsuka ; Igarashi, Hisato. / The up-to-date review of epidemiological pancreatic neuroendocrine tumors in Japan. :: Journal of Hepato-Biliary-Pancreatic Sciences. 2015 ; 巻 22, 番号 8. pp. 574-577.
@article{cc1f1fe2fae84879b03450c545b06796,
title = "The up-to-date review of epidemiological pancreatic neuroendocrine tumors in Japan",
abstract = "Pancreatic neuroendocrine tumors (PNETs) were considered an extremely rare disease. However, in recent years, the number of patients with PNET has increased rapidly. According to an epidemiological survey conducted in Japan, the number of treated patients with PNETs in 2010 was approximately 1.2-times that in 2005, and the number of new incidences of non-functional PNETs in 2010 was approximately 1.7-times that in 2005. Among functional PNETs, insulinoma was most prevalent, followed by gastrinoma. To diagnose PNETs, correct histological diagnosis is most important. According to the World Health Organization 2010 classification criteria, neuroendocrine tumors (NETs) are categorized into well-differentiated NETs and poorly differentiated neuroendocrine carcinomas (NECs). NECs accounted for 7.6{\%} of all NETs, and functional and non-functional PNETs accounted for 2.1{\%} and 10.1{\%}, respectively. Patients with distant metastasis accounted for 19.9{\%}, and those with multiple endocrine neoplasia type 1 accounted for 4.3{\%}. When treating PNETs, it is necessary to correctly evaluate the functionality and progression of tumors, the presence or absence of metastasis, and the degrees of differentiation and malignant potential of tumors. A new registration system from the Japan Neuroendocrine Tumor Society will start to be used in 2015, which will help further dissemination of Japanese epidemiological information to the world.",
author = "Tetsuhide Ito and Lingaku Lee and Masayuki Hijioka and Ken Kawabe and Masaki Kato and Kazuhiko Nakamura and Keijiro Ueda and Ohtsuka Takao and Hisato Igarashi",
year = "2015",
month = "8",
day = "1",
doi = "10.1002/jhbp.225",
language = "English",
volume = "22",
pages = "574--577",
journal = "Journal of Hepato-Biliary-Pancreatic Sciences",
issn = "1868-6974",
publisher = "Springer Verlag",
number = "8",

}

TY - JOUR

T1 - The up-to-date review of epidemiological pancreatic neuroendocrine tumors in Japan

AU - Ito, Tetsuhide

AU - Lee, Lingaku

AU - Hijioka, Masayuki

AU - Kawabe, Ken

AU - Kato, Masaki

AU - Nakamura, Kazuhiko

AU - Ueda, Keijiro

AU - Takao, Ohtsuka

AU - Igarashi, Hisato

PY - 2015/8/1

Y1 - 2015/8/1

N2 - Pancreatic neuroendocrine tumors (PNETs) were considered an extremely rare disease. However, in recent years, the number of patients with PNET has increased rapidly. According to an epidemiological survey conducted in Japan, the number of treated patients with PNETs in 2010 was approximately 1.2-times that in 2005, and the number of new incidences of non-functional PNETs in 2010 was approximately 1.7-times that in 2005. Among functional PNETs, insulinoma was most prevalent, followed by gastrinoma. To diagnose PNETs, correct histological diagnosis is most important. According to the World Health Organization 2010 classification criteria, neuroendocrine tumors (NETs) are categorized into well-differentiated NETs and poorly differentiated neuroendocrine carcinomas (NECs). NECs accounted for 7.6% of all NETs, and functional and non-functional PNETs accounted for 2.1% and 10.1%, respectively. Patients with distant metastasis accounted for 19.9%, and those with multiple endocrine neoplasia type 1 accounted for 4.3%. When treating PNETs, it is necessary to correctly evaluate the functionality and progression of tumors, the presence or absence of metastasis, and the degrees of differentiation and malignant potential of tumors. A new registration system from the Japan Neuroendocrine Tumor Society will start to be used in 2015, which will help further dissemination of Japanese epidemiological information to the world.

AB - Pancreatic neuroendocrine tumors (PNETs) were considered an extremely rare disease. However, in recent years, the number of patients with PNET has increased rapidly. According to an epidemiological survey conducted in Japan, the number of treated patients with PNETs in 2010 was approximately 1.2-times that in 2005, and the number of new incidences of non-functional PNETs in 2010 was approximately 1.7-times that in 2005. Among functional PNETs, insulinoma was most prevalent, followed by gastrinoma. To diagnose PNETs, correct histological diagnosis is most important. According to the World Health Organization 2010 classification criteria, neuroendocrine tumors (NETs) are categorized into well-differentiated NETs and poorly differentiated neuroendocrine carcinomas (NECs). NECs accounted for 7.6% of all NETs, and functional and non-functional PNETs accounted for 2.1% and 10.1%, respectively. Patients with distant metastasis accounted for 19.9%, and those with multiple endocrine neoplasia type 1 accounted for 4.3%. When treating PNETs, it is necessary to correctly evaluate the functionality and progression of tumors, the presence or absence of metastasis, and the degrees of differentiation and malignant potential of tumors. A new registration system from the Japan Neuroendocrine Tumor Society will start to be used in 2015, which will help further dissemination of Japanese epidemiological information to the world.

UR - http://www.scopus.com/inward/record.url?scp=84937523495&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84937523495&partnerID=8YFLogxK

U2 - 10.1002/jhbp.225

DO - 10.1002/jhbp.225

M3 - Article

C2 - 25689058

AN - SCOPUS:84937523495

VL - 22

SP - 574

EP - 577

JO - Journal of Hepato-Biliary-Pancreatic Sciences

JF - Journal of Hepato-Biliary-Pancreatic Sciences

SN - 1868-6974

IS - 8

ER -