Thermal separation: Interplay between the soret effect and entropic force gradient

Yusuke T. Maeda, Axel Buguin, Albert Libchaber

研究成果: ジャーナルへの寄稿学術誌査読

62 被引用数 (Scopus)

抄録

Thermophoresis, the Soret effect, depletes a high concentration of a polyethylene glycol polymer solution from the hot region and builds a concentration gradient. In such a solution, solutes of small concentration experience thermophoresis and polyethylene glycol concentration-dependent restoring forces. We report that by using focused laser heating and varying the polyethylene glycol concentration one observes geometrical localizations of solutes like DNA and RNA into patterns such as a ring. For DNA up to 5.6 kbp, the ring size decreases following a behavior analogous to a gel electrophoresis separation. Above 5.6 kbp, the ring diameter increases with the DNA length. Mixtures of DNA and RNA can be separated as well as different RNA lengths. Separation of colloids is also observed. The experiments might be relevant for the separation of small RNA ribozymes in an early stage of life.

本文言語英語
論文番号038301
ジャーナルPhysical review letters
107
3
DOI
出版ステータス出版済み - 7月 11 2011
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 物理学および天文学(全般)

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