Thermo responsive DNA/polymer conjugate for intelligent antisense strategy

Masaharu Murata, Wataru Kaku, Takahisa Anada, Nobuaki Soh, Yoshiki Katayama, Mizuo Maeda

研究成果: ジャーナルへの寄稿記事

19 引用 (Scopus)

抄録

The conjugate between 20-mer antisense oligodeoxynucleotides (ODN) and thermo-responsive polymer, poly(N-isopropylacrylamide) (PNIPAAm), was prepared. Hybridization reaction between the conjugate and their target RNA was modulated by conformational change of polymer moiety depending on temperature condition.

元の言語英語
ページ(範囲)266-267
ページ数2
ジャーナルChemistry Letters
32
発行部数3
DOI
出版物ステータス出版済み - 3 5 2003

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Polymers
Oligodeoxyribonucleotides
DNA
RNA
Temperature
poly-N-isopropylacrylamide

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

これを引用

Thermo responsive DNA/polymer conjugate for intelligent antisense strategy. / Murata, Masaharu; Kaku, Wataru; Anada, Takahisa; Soh, Nobuaki; Katayama, Yoshiki; Maeda, Mizuo.

:: Chemistry Letters, 巻 32, 番号 3, 05.03.2003, p. 266-267.

研究成果: ジャーナルへの寄稿記事

Murata, Masaharu ; Kaku, Wataru ; Anada, Takahisa ; Soh, Nobuaki ; Katayama, Yoshiki ; Maeda, Mizuo. / Thermo responsive DNA/polymer conjugate for intelligent antisense strategy. :: Chemistry Letters. 2003 ; 巻 32, 番号 3. pp. 266-267.
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