抄録
Lipo-VPGVG2 was synthesized by the conjugation of elastin model peptide of (Val-Pro-Gly-Val-Gly)2 and a-hpoic acid. The peptide showed some changes of conformation and water solubility in the aqueous solution. The DSC results suggested the thermoresponsive transition with temperature. The peptide of Lipo-VPGVG2 was dissolved in aqueous solution, and the gold substrate was immersed in the LipoVPGVG2 solution in order to prepare the self-assembled monolayer (SAM). The SAM formation was confirmed by FTIR, XPS, and QCM. The cell attachment of fibroblast NIH 3T3 was observed on the Lipo-VPGVG2-SAM materials prepared by the dilute peptide solutions (20 and 80 nM). The cell detachment was observed on cooling the peptide SAM at 4°C. The Lipo-VPGVG2 showed a thermoresponsive biofunction.
本文言語 | 英語 |
---|---|
ページ(範囲) | 584-589 |
ページ数 | 6 |
ジャーナル | KOBUNSHI RONBUNSHU |
巻 | 67 |
号 | 10 |
DOI | |
出版ステータス | 出版済み - 10月 2010 |
!!!All Science Journal Classification (ASJC) codes
- 化学工学(その他)
- 材料科学(その他)
- 環境科学(全般)
- ポリマーおよびプラスチック