Thermoresponsive polymer brush surfaces with hydrophobic groups for all-aqueous chromatography

Kenichi Nagase, Mio Kumazaki, Hideko Kanazawa, Jun Kobayashi, Akihiko Kikuci, Yoshikatsu Akiyama, Annaka Masahiko, Teruo Okano

研究成果: ジャーナルへの寄稿記事

44 引用 (Scopus)

抄録

For developing thermoresponsive chromatographic matrices with a strong hydrophobicity, poly(N-isopropylacrylamide-co-n-butyl methacrylate) (poly(IPAAm-co-BMA)) brush grafted silica beads were prepared through a surface-initiated atom transfer radical polymerization (ATRP) with a CuCl/CuCl2/Me6TREN catalytic system in 2-propanol at 25 °C for 16 h. The prepared beads were characterized by chromatographic analysis. Chromatograms of the benzoic-acid family and phenol as model analytes were obtained with high-resolution peaks because of their strong hydrophobic interactions to the densely grafted hydrophobized copolymers on the beads. Retention times of the analytes increased with the increase in BMA composition ratio. Dehydration of grafted copolymer with large BMA composition was performed at low temperature. These results indicated that the copolymer-brush-grafted surface prepared by ATRP was an effective tool for separating hydrophilic analytes at low temperature through modulating the strong hydrophobic interaction.

元の言語英語
ページ(範囲)1247-1253
ページ数7
ジャーナルACS Applied Materials and Interfaces
2
発行部数4
DOI
出版物ステータス出版済み - 4 28 2010

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Brushes
Chromatography
Polymers
Copolymers
Atom transfer radical polymerization
Chromatographic analysis
Benzoic Acid
2-Propanol
Benzoic acid
Propanol
Hydrophobicity
Phenol
Chemical analysis
Dehydration
Silicon Dioxide
Phenols
Silica
Temperature

All Science Journal Classification (ASJC) codes

  • Materials Science(all)

これを引用

Nagase, K., Kumazaki, M., Kanazawa, H., Kobayashi, J., Kikuci, A., Akiyama, Y., ... Okano, T. (2010). Thermoresponsive polymer brush surfaces with hydrophobic groups for all-aqueous chromatography. ACS Applied Materials and Interfaces, 2(4), 1247-1253. https://doi.org/10.1021/am100122h

Thermoresponsive polymer brush surfaces with hydrophobic groups for all-aqueous chromatography. / Nagase, Kenichi; Kumazaki, Mio; Kanazawa, Hideko; Kobayashi, Jun; Kikuci, Akihiko; Akiyama, Yoshikatsu; Masahiko, Annaka; Okano, Teruo.

:: ACS Applied Materials and Interfaces, 巻 2, 番号 4, 28.04.2010, p. 1247-1253.

研究成果: ジャーナルへの寄稿記事

Nagase, K, Kumazaki, M, Kanazawa, H, Kobayashi, J, Kikuci, A, Akiyama, Y, Masahiko, A & Okano, T 2010, 'Thermoresponsive polymer brush surfaces with hydrophobic groups for all-aqueous chromatography', ACS Applied Materials and Interfaces, 巻. 2, 番号 4, pp. 1247-1253. https://doi.org/10.1021/am100122h
Nagase, Kenichi ; Kumazaki, Mio ; Kanazawa, Hideko ; Kobayashi, Jun ; Kikuci, Akihiko ; Akiyama, Yoshikatsu ; Masahiko, Annaka ; Okano, Teruo. / Thermoresponsive polymer brush surfaces with hydrophobic groups for all-aqueous chromatography. :: ACS Applied Materials and Interfaces. 2010 ; 巻 2, 番号 4. pp. 1247-1253.
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AU - Masahiko, Annaka

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