Thermosensitive micelles composed of poly(lactide)-G-poly(NIPAM-CO-HEMA) graft copolymers

Tran Minh Quynh, Masaru Yoneyama, Yasuyuki Maki, Naotsugu Nagasawa, Toshiaki Dobashi

研究成果: 書籍/レポート タイプへの寄稿会議への寄与

3 被引用数 (Scopus)

抄録

Different poly(N-isopropylacrylamide-co-hydroxyethyl methacrylate) copolymers (P(NIPAM-co-HEMA)) were synthesized from N-isopropylacrylamide (NIPA) and hydroxyethyl methacrylate (HEMA) comonomers by both radical and radiation polymerizations for comparison. PLLA-g-P(NIPAM-co-HEMA) graft copolymers were synthesized from L-lactide and respective P(NIPAM-co-HEMA) copolymers by ring opening polymerization. Both NMR and FTIR analyses demonstrated the PLLA chains have been grafted on to the P(NIPAM-co-HEMA) backbone. These graft copolymers revealed the cloud point temperature higher than that of PNIPAM homopolymer as determined by optical transmittance. The graft copolymers self-assembled into micelles with regularly spherical structures as observed by atomic force microscopy (AFM). The properties of these graft copolymers are interesting for the drug delivery system.

本文言語英語
ホスト出版物のタイトルSilicon Science and Advanced Micro-Device Engineering I
ページ51-56
ページ数6
DOI
出版ステータス出版済み - 1月 20 2011
外部発表はい
イベント5th International Symposium on Silicon Science, ISSS 2009 and the 1st International Conference on Advanced Micro-Device Engineering, AMDE 2009 - Kiryu, 日本
継続期間: 12月 10 200912月 11 2009

出版物シリーズ

名前Key Engineering Materials
459
ISSN(印刷版)1013-9826

その他

その他5th International Symposium on Silicon Science, ISSS 2009 and the 1st International Conference on Advanced Micro-Device Engineering, AMDE 2009
国/地域日本
CityKiryu
Period12/10/0912/11/09

!!!All Science Journal Classification (ASJC) codes

  • 材料科学(全般)
  • 材料力学
  • 機械工学

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