@article{f75f1cfd788440448cdddb11f5a2790b,
title = "Thiazolobenzyne: A versatile intermediate for multisubstituted benzothiazoles",
abstract = "Thiazolobenzyne, which is a benzyne species fused with a thiazole ring, was efficiently generated via an iodine-magnesium exchange reaction of an ortho-iodoaryl triflate-type precursor using a trimethylsilylmethyl Grignard reagent as an activator. A wide range of arynophiles reacted efficiently with the thiazolobenzynes generated by this method to afford various multisubstituted benzothiazoles.",
author = "Suguru Yoshida and Takahisa Yano and Yoshitake Nishiyama and Yoshihiro Misawa and Masakazu Kondo and Takeshi Matsushita and Kazunobu Igawa and Katsuhiko Tomooka and Takamitsu Hosoya",
note = "Funding Information: This work was supported by the Platform for Drug Discovery, Informatics, and Structural Life Science from MEXT and AMED, Japan; CREST from JST and AMED, Japan; JSPS KAKENHI Grant Numbers 15H03118 (B; T. H.), 16H01133 (Middle Molecular Strategy; T. H.) and 26350971 (C; S. Y.); and the Cooperative Research Program of Network Joint Research Center for Materials and Devices. Publisher Copyright: {\textcopyright} 2016 The Royal Society of Chemistry.",
year = "2016",
doi = "10.1039/c6cc05112j",
language = "English",
volume = "52",
pages = "11199--11202",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "75",
}