Threshold of Application of Antidepressant Drugs for Treatment of Depressive Disorder

Toshihide Kuroki, Teppei Tanaka

研究成果: ジャーナルへの寄稿評論記事

抄録

In recent years, along with the expansion of medical care for depressive disorder, there has been much controversy regarding the application of antidepressant drugs for its treatment. The aim of this paper is to consider critical issues concerning the threshold of application of antidepressant drugs for the treatment of depression. It was formerly important to diagnose the 'quality' of depression (melancholia or non-melancholia) in order to choose antidepressant treatment, whereas an assessment of the 'quantity' of depression (severity of symptoms) is crucial today to decide on the threshold. Recent guidelines for the treatment of major depressive disorder do not positively recommend the use of medication for the treatment of mild depression. The guidelines published by the Japanese Society of Mood Disorders also state that doctors have to give priority to treatments avoiding medication, although the effectiveness of antidepressant drugs for mild depression is controversial. Actually, in a clinical setting, doctors have to understand the conditions of individual cases and cope with many issues, such as a risk of suicide, comorbidity of other psychiatric disorders, target symptoms of pharmacotherapy, and choices of classes and doses of antidepressant drugs. The threshold of application of antidepressant drugs for the treatment of depression may vary according to the doctor-patient relationship and surrounding conditions. Doctors are required to provide treatment options other than pharmacotherapy.

元の言語英語
ページ(範囲)269-276
ページ数8
ジャーナルSeishin shinkeigaku zasshi = Psychiatria et neurologia Japonica
117
発行部数4
出版物ステータス出版済み - 1 1 2015

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Depressive Disorder
Antidepressive Agents
Depression
Therapeutics
Guidelines
Drug Therapy
Major Depressive Disorder
Mood Disorders
Suicide
Psychiatry
Comorbidity

All Science Journal Classification (ASJC) codes

  • Medicine(all)

これを引用

Threshold of Application of Antidepressant Drugs for Treatment of Depressive Disorder. / Kuroki, Toshihide; Tanaka, Teppei.

:: Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 巻 117, 番号 4, 01.01.2015, p. 269-276.

研究成果: ジャーナルへの寄稿評論記事

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