Time-dependent mechanical behaviors of articular cartilage and chondrocytes under constant total compressive deformation

T. Murakami, N. Sakai, Y. Sawae, Y. Kurohara, I. Ishikawa, M. Okamoto

研究成果: Chapter in Book/Report/Conference proceedingChapter

2 被引用数 (Scopus)

抄録

The excellent performance of very low friction and long durability of natural synovial joints is maintained with synergistic metabolism of articular cartilage and synovial fluid. To study metabolic mechanism including repair process, it is important to know the stress-strain state of the cartilage and extracellular matrix around chondrocytes during cartilage deformation, where chondrocytes seem to experience similar deformation to extracellular matrix. The articular cartilage of high water content has a biphasic viscoelastic property and shows the time-dependent deformation behavior. In this study, the compressive behaviors in articular cartilage containing chondrocytes were observed in the compressive apparatus located in the stage of confocal laser scanning microscope. The time-dependent behavior of articular cartilage was evaluated by the finite element method for biphasic model.

本文言語英語
ホスト出版物のタイトルBiomechanics at Micro- and Nanoscale Levels
出版社World Scientific Publishing Co.
ページ37-47
ページ数11
2
ISBN(電子版)9789812773838
ISBN(印刷版)9812567461, 9789812567468
DOI
出版ステータス出版済み - 1 1 2006

All Science Journal Classification (ASJC) codes

  • 生化学、遺伝学、分子生物学(全般)

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