抄録
Organ culture systems are used to elucidate the mechanisms of pattern formation in developmental biology. Various organ culture techniques have been used, but the lack of microcirculation in such cultures impedes the long-term maintenance of larger tissues. Recent advances in microfluidic devices now enable us to utilize self-organized perfusable capillary networks in organ cultures. In this review, we will overview past approaches to organ culture and current technical advances in microfluidic devices, and discuss possible applications of microfluidics towards the study of developmental biology.
| 元の言語 | 英語 |
|---|---|
| ページ（範囲） | 505-515 |
| ページ数 | 11 |
| ジャーナル | Development Growth and Differentiation |
| 巻 | 58 |
| 発行部数 | 6 |
| DOI | |
| 出版物ステータス | 出版済み - 8 1 2016 |
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All Science Journal Classification (ASJC) codes
- Developmental Biology
- Cell Biology
これを引用
Tissue culture on a chip : Developmental biology applications of self-organized capillary networks in microfluidic devices. / Miura, Takashi; Yokokawa, Ryuji.
：: Development Growth and Differentiation, 巻 58, 番号 6, 01.08.2016, p. 505-515.研究成果: ジャーナルへの寄稿 › 評論記事
}
TY - JOUR
T1 - Tissue culture on a chip
T2 - Developmental biology applications of self-organized capillary networks in microfluidic devices
AU - Miura, Takashi
AU - Yokokawa, Ryuji
PY - 2016/8/1
Y1 - 2016/8/1
N2 - Organ culture systems are used to elucidate the mechanisms of pattern formation in developmental biology. Various organ culture techniques have been used, but the lack of microcirculation in such cultures impedes the long-term maintenance of larger tissues. Recent advances in microfluidic devices now enable us to utilize self-organized perfusable capillary networks in organ cultures. In this review, we will overview past approaches to organ culture and current technical advances in microfluidic devices, and discuss possible applications of microfluidics towards the study of developmental biology.
AB - Organ culture systems are used to elucidate the mechanisms of pattern formation in developmental biology. Various organ culture techniques have been used, but the lack of microcirculation in such cultures impedes the long-term maintenance of larger tissues. Recent advances in microfluidic devices now enable us to utilize self-organized perfusable capillary networks in organ cultures. In this review, we will overview past approaches to organ culture and current technical advances in microfluidic devices, and discuss possible applications of microfluidics towards the study of developmental biology.
UR - http://www.scopus.com/inward/record.url?scp=84978811122&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84978811122&partnerID=8YFLogxK
U2 - 10.1111/dgd.12292
DO - 10.1111/dgd.12292
M3 - Review article
C2 - 27272910
AN - SCOPUS:84978811122
VL - 58
SP - 505
EP - 515
JO - Development Growth and Differentiation
JF - Development Growth and Differentiation
SN - 0012-1592
IS - 6
ER -