To use the brief psychiatric rating scale to detect disorganized speech in schizophrenia: Findings from the REAP-AP study

Yong Chon Park, Shigenobu Kanba, Mian Yoon Chong, Adarsh Tripathi, Roy Abraham Kallivayalil, Ajit Avasthi, Sandeep Grover, Kok Yoon Chee, Andi J. Tanra, Marigarita M. Maramis, Shu Yu Yang, Norman Sartorius, Chay Hoon Tan, Naotaka Shinfuku, Seon Cheol Park

研究成果: Contribution to journalArticle

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Our study aimed to assess the psychometric validity of the conceptual disorganization item and other items of the Brief Psychiatric Rating Scale (BPRS) for detecting disorganized speech in patients with schizophrenia. We included 357 schizophrenia patients with disorganized speech and 1082 without disorganized speech from the survey centers in India, Indonesia, Japan, Malaysia, and Taiwan, using the data from the Research on Asian Psychotropic Patterns for Antipsychotics (REAP-AP) study. After adjusting the effects of confounding variables, a binary logistic regression model was fitted to identify BPRS items independently associated with disorganized speech. Receiver operating characteristic (ROC) curves were used to identify optimum cut-off scores and their sensitivities and specificities for detecting disorganized speech. After adjusting the effects of confounding variables, the fitted binary logistic regression model indicated that conceptual disorganization (P < 0.0001), uncooperativeness (P = 0.010) and excitement (P = 0.001) were independently associated with disorganized speech. The ROC curve revealed that the conceptual disorganization item could accurately detect disorganized speech in patients with schizophrenia both separately and in combination with uncooperativeness and excitement. The subscale for conceptual disorganization, uncooperativeness and excitement items in the BPRS is a promising psychometric tool for detecting disorganized speech.

元の言語英語
ページ(範囲)113-119
ページ数7
ジャーナルKaohsiung Journal of Medical Sciences
34
発行部数2
DOI
出版物ステータス出版済み - 2 2018

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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    Chon Park, Y., Kanba, S., Chong, M. Y., Tripathi, A., Kallivayalil, R. A., Avasthi, A., Grover, S., Chee, K. Y., J. Tanra, A., Maramis, M. M., Yang, S. Y., Sartorius, N., Tan, C. H., Shinfuku, N., & Park, S. C. (2018). To use the brief psychiatric rating scale to detect disorganized speech in schizophrenia: Findings from the REAP-AP study. Kaohsiung Journal of Medical Sciences, 34(2), 113-119. https://doi.org/10.1016/j.kjms.2017.09.009