Topographic mapping--the olfactory system.

Takeshi Imai, Hitoshi Sakano, Leslie B. Vosshall

研究成果: ジャーナルへの寄稿評論記事

51 引用 (Scopus)

抄録

Sensory systems must map accurate representations of the external world in the brain. Although the physical senses of touch and vision build topographic representations of the spatial coordinates of the body and the field of view, the chemical sense of olfaction maps discontinuous features of chemical space, comprising an extremely large number of possible odor stimuli. In both mammals and insects, olfactory circuits are wired according to the convergence of axons from sensory neurons expressing the same odorant receptor. Synapses are organized into distinctive spherical neuropils--the olfactory glomeruli--that connect sensory input with output neurons and local modulatory interneurons. Although there is a strong conservation of form in the olfactory maps of mammals and insects, they arise using divergent mechanisms. Olfactory glomeruli provide a unique solution to the problem of mapping discontinuous chemical space onto the brain.

元の言語英語
ジャーナルCold Spring Harbor Perspectives in Biology
2
発行部数8
DOI
出版物ステータス出版済み - 8 1 2010

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Olfactory Bulb
Insects
Mammals
Odorant Receptors
Neurons
Neuropil
Smell
Brain
Touch
Interneurons
Sensory Receptor Cells
Synapses
Axons
Odors
Conservation
Networks (circuits)
Odorants

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

これを引用

Topographic mapping--the olfactory system. / Imai, Takeshi; Sakano, Hitoshi; Vosshall, Leslie B.

:: Cold Spring Harbor Perspectives in Biology, 巻 2, 番号 8, 01.08.2010.

研究成果: ジャーナルへの寄稿評論記事

Imai, Takeshi ; Sakano, Hitoshi ; Vosshall, Leslie B. / Topographic mapping--the olfactory system. :: Cold Spring Harbor Perspectives in Biology. 2010 ; 巻 2, 番号 8.
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