Intramolecular acylation of an organolithium leads to an efficient stereocontrolled total synthesis of both enantiomers of sundiversifolide. The absolute configuration was determined by HPLC analysis and allelopathy assay. The y-lactone moiety resulted from a butenolide was obtained by the condensation of a bicyclic a-hydroxyhemiacetal with Ph3P=CMe(CO2R).
All Science Journal Classification (ASJC) codes
- Physical and Theoretical Chemistry
- Organic Chemistry