Transarterial immuno-embolization therapy in patients with hepatocellular carcinoma

H. Eguchi, T. Takeda, M. Sakon, K. Umeshita, H. Ohzato, K. Dono, M. Gotoh, T. Monden, M. Monden

研究成果: Contribution to journalArticle査読


Surgical resection, transcatheter arterial embolization (TAE) and percutaneous ethanol injection therapy (PEIT) are effective for hepatocellular carcinoma (HCC), but the recurrence rate is high. We have devised a new therapy of transarterial immuno-embolization (TIE) with OK- 432, fibrinogen and thrombin, and 2 cases are reported. Case 1:A 78-year-old Japanese male with HCC (diameter, 4 cm in subsegment 5) received TIE. The tumor size was markedly decreased, and the patient survived for more than 3 years without recurrence. Case 2: A 61-year-old Japanese male with HCC (diameter, 4.5 cm in segment 5) received hepatic subsegmentectomy following TIE. Histological examination of resected specimens following TIE showed massive infiltration of mononuclear cells in the main tumor. Tumor recurrence had developed three times thereafter, but was effectively treated by TIE. TIE may be an effective therapy for HCC.

ジャーナルJapanese Journal of Cancer and Chemotherapy
出版ステータス出版済み - 12 8 1997

All Science Journal Classification (ASJC) codes

  • 腫瘍学
  • 癌研究


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