Transcription factors and drug resistance

Kimitoshi Kohno, Takeshi Uchiumi, Ichiro Niina, Tetsuro Wakasugi, Tomonori Igarashi, Yasutomo Momii, Takeshi Yoshida, Ken Ichi Matsuo, Naoya Miyamoto, Hiroto Izumi

研究成果: ジャーナルへの寄稿記事

56 引用 (Scopus)

抄録

Intrinsic or acquired resistance to anticancer agents is a major obstacle to the success of chemotherapy. Anticancer agents are known to modulate signal transduction pathways and alter expression of genes that play an important role in drug resistance. Emerging evidence suggests that the complexity of genomic response against anticancer agents arise from elaborate gene expression by multiple transcription factors. Here, we briefly describe the development of solid tumours and the appearance of drug-resistant cells. We also review what is known of the transcription factors that are involved in resistance to drugs, particularly cisplatin.

元の言語英語
ページ(範囲)2577-2586
ページ数10
ジャーナルEuropean Journal of Cancer
41
発行部数16
DOI
出版物ステータス出版済み - 1 1 2005
外部発表Yes

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Drug Resistance
Antineoplastic Agents
Transcription Factors
Gene Expression
Cisplatin
Signal Transduction
Drug Therapy
Pharmaceutical Preparations
Neoplasms

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

これを引用

Kohno, K., Uchiumi, T., Niina, I., Wakasugi, T., Igarashi, T., Momii, Y., ... Izumi, H. (2005). Transcription factors and drug resistance. European Journal of Cancer, 41(16), 2577-2586. https://doi.org/10.1016/j.ejca.2005.08.007

Transcription factors and drug resistance. / Kohno, Kimitoshi; Uchiumi, Takeshi; Niina, Ichiro; Wakasugi, Tetsuro; Igarashi, Tomonori; Momii, Yasutomo; Yoshida, Takeshi; Matsuo, Ken Ichi; Miyamoto, Naoya; Izumi, Hiroto.

:: European Journal of Cancer, 巻 41, 番号 16, 01.01.2005, p. 2577-2586.

研究成果: ジャーナルへの寄稿記事

Kohno, K, Uchiumi, T, Niina, I, Wakasugi, T, Igarashi, T, Momii, Y, Yoshida, T, Matsuo, KI, Miyamoto, N & Izumi, H 2005, 'Transcription factors and drug resistance', European Journal of Cancer, 巻. 41, 番号 16, pp. 2577-2586. https://doi.org/10.1016/j.ejca.2005.08.007
Kohno K, Uchiumi T, Niina I, Wakasugi T, Igarashi T, Momii Y その他. Transcription factors and drug resistance. European Journal of Cancer. 2005 1 1;41(16):2577-2586. https://doi.org/10.1016/j.ejca.2005.08.007
Kohno, Kimitoshi ; Uchiumi, Takeshi ; Niina, Ichiro ; Wakasugi, Tetsuro ; Igarashi, Tomonori ; Momii, Yasutomo ; Yoshida, Takeshi ; Matsuo, Ken Ichi ; Miyamoto, Naoya ; Izumi, Hiroto. / Transcription factors and drug resistance. :: European Journal of Cancer. 2005 ; 巻 41, 番号 16. pp. 2577-2586.
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