Transformation of follicular lymphoma to double-hit lymphoma during adjuvant chemotherapy for concurrent ovarian carcinoma

Taisuke Narazaki, Yasuhiro Nakashima, Yasuhiro Tsukamoto, Mariko Tsuda, Toru Masuda, Daisaku Kimura, Akiko Takamatsu, Koichi Ohshima, Motoaki Shiratsuchi, Yoshihiro Ogawa

研究成果: Contribution to journalArticle査読

抄録

The frequency of multiple primary malignant neoplasms (MPMN) is increasing due to population aging. Since consensus guidelines for the treatment of MPMN are lacking, treatment strategies are determined by disease status on a per-patient basis. In this report, we describe a case of MPMN with follicular lymphoma (FL) grade 1 that transformed to double-hit lymphoma during adjuvant chemotherapy for concurrent ovarian carcinoma. A 64-year-old woman was diagnosed with MPMN of FL and endometrioid carcinoma by staging laparotomy and lymph node biopsy. She received four cycles of adjuvant chemotherapy (carboplatin and paclitaxel) for endometrioid carcinoma, but during chemotherapy, the FL grade 1 transformed to double-hit lymphoma. We speculate that adjuvant chemotherapy for endometrioid carcinoma may have triggered the transformation of FL in the present case.

本文言語英語
ページ(範囲)375-380
ページ数6
ジャーナルInternational journal of hematology
110
3
DOI
出版ステータス出版済み - 9 20 2019

All Science Journal Classification (ASJC) codes

  • Hematology

フィンガープリント 「Transformation of follicular lymphoma to double-hit lymphoma during adjuvant chemotherapy for concurrent ovarian carcinoma」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

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