抄録
The frequency of multiple primary malignant neoplasms (MPMN) is increasing due to population aging. Since consensus guidelines for the treatment of MPMN are lacking, treatment strategies are determined by disease status on a per-patient basis. In this report, we describe a case of MPMN with follicular lymphoma (FL) grade 1 that transformed to double-hit lymphoma during adjuvant chemotherapy for concurrent ovarian carcinoma. A 64-year-old woman was diagnosed with MPMN of FL and endometrioid carcinoma by staging laparotomy and lymph node biopsy. She received four cycles of adjuvant chemotherapy (carboplatin and paclitaxel) for endometrioid carcinoma, but during chemotherapy, the FL grade 1 transformed to double-hit lymphoma. We speculate that adjuvant chemotherapy for endometrioid carcinoma may have triggered the transformation of FL in the present case.
| 元の言語 | 英語 |
|---|---|
| ページ（範囲） | 375-380 |
| ページ数 | 6 |
| ジャーナル | International journal of hematology |
| 巻 | 110 |
| 発行部数 | 3 |
| DOI | |
| 出版物ステータス | 出版済み - 9 20 2019 |
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All Science Journal Classification (ASJC) codes
- Hematology
これを引用
Transformation of follicular lymphoma to double-hit lymphoma during adjuvant chemotherapy for concurrent ovarian carcinoma. / Narazaki, Taisuke; Nakashima, Yasuhiro; Tsukamoto, Yasuhiro; Tsuda, Mariko; Masuda, Toru; Kimura, Daisaku; Takamatsu, Akiko; Ohshima, Koichi; Shiratsuchi, Motoaki; Ogawa, Yoshihiro.
：: International journal of hematology, 巻 110, 番号 3, 20.09.2019, p. 375-380.研究成果: ジャーナルへの寄稿 › 記事
}
TY - JOUR
T1 - Transformation of follicular lymphoma to double-hit lymphoma during adjuvant chemotherapy for concurrent ovarian carcinoma
AU - Narazaki, Taisuke
AU - Nakashima, Yasuhiro
AU - Tsukamoto, Yasuhiro
AU - Tsuda, Mariko
AU - Masuda, Toru
AU - Kimura, Daisaku
AU - Takamatsu, Akiko
AU - Ohshima, Koichi
AU - Shiratsuchi, Motoaki
AU - Ogawa, Yoshihiro
PY - 2019/9/20
Y1 - 2019/9/20
N2 - The frequency of multiple primary malignant neoplasms (MPMN) is increasing due to population aging. Since consensus guidelines for the treatment of MPMN are lacking, treatment strategies are determined by disease status on a per-patient basis. In this report, we describe a case of MPMN with follicular lymphoma (FL) grade 1 that transformed to double-hit lymphoma during adjuvant chemotherapy for concurrent ovarian carcinoma. A 64-year-old woman was diagnosed with MPMN of FL and endometrioid carcinoma by staging laparotomy and lymph node biopsy. She received four cycles of adjuvant chemotherapy (carboplatin and paclitaxel) for endometrioid carcinoma, but during chemotherapy, the FL grade 1 transformed to double-hit lymphoma. We speculate that adjuvant chemotherapy for endometrioid carcinoma may have triggered the transformation of FL in the present case.
AB - The frequency of multiple primary malignant neoplasms (MPMN) is increasing due to population aging. Since consensus guidelines for the treatment of MPMN are lacking, treatment strategies are determined by disease status on a per-patient basis. In this report, we describe a case of MPMN with follicular lymphoma (FL) grade 1 that transformed to double-hit lymphoma during adjuvant chemotherapy for concurrent ovarian carcinoma. A 64-year-old woman was diagnosed with MPMN of FL and endometrioid carcinoma by staging laparotomy and lymph node biopsy. She received four cycles of adjuvant chemotherapy (carboplatin and paclitaxel) for endometrioid carcinoma, but during chemotherapy, the FL grade 1 transformed to double-hit lymphoma. We speculate that adjuvant chemotherapy for endometrioid carcinoma may have triggered the transformation of FL in the present case.
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U2 - 10.1007/s12185-019-02656-4
DO - 10.1007/s12185-019-02656-4
M3 - Article
AN - SCOPUS:85066095083
VL - 110
SP - 375
EP - 380
JO - International Journal of Hematology
JF - International Journal of Hematology
SN - 0925-5710
IS - 3
ER -