Translational research on neuropsychiatrie disorders: Focusing on microglia hypothesis

Takahiro A. Kato, Masahiro Ohgidani, Shigenobu Kanba

研究成果: Contribution to journalArticle査読

1 被引用数 (Scopus)

抄録

Microglia - immune cells in the brain - have recently been highlighted to understand the pathophysiology of psychiatric disorders such as schizophrenia, depression, and autism. In this review paper, we introduce the microglia hypothesis for psychiatric disorders. In addition, we introduce our novel translational research approach to psychiatric disorders using microglia-like (iMG) cells directly induced from human blood, these iMG cells can be produced from peripheral monocytes within two weeks using two cytokines: granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-34 (IL-34).

本文言語英語
ページ(範囲)1007-1015
ページ数9
ジャーナルBrain and Nerve
69
9
出版ステータス出版済み - 9 2017

All Science Journal Classification (ASJC) codes

  • 臨床神経学

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