Traumatic neuroma of the lower lip with intraepithelial nerve fibers

Akari Tashiro, Shinichi Imafuku, Masutaka Furue

研究成果: Contribution to journalArticle査読

5 被引用数 (Scopus)


A 42-year-old man had noticed a small tender papule on his lower lip, and the papule clinically became unnoticeable after cryosurgery. He visited our clinic because the lesion recurred up to the original size after 9 months. On examination, a linear scar and a papule, 4 mm in diameter, were observed on the mucosal lower lip. The papule was resected and histopathologically showed proliferation of nerve fibers in irregular and tortuous fascicles, thus establishing the diagnosis of traumatic neuroma. Immunohistochemical staining by antineuron-specific enolase (NSE) antibody showed proliferation of axons in the upper lamina propria and even in the mucosal epithelium overlying the tumor. Traumatic neuroma of the lower lip is very rare, and a literature search showed only one reported case. Intraepithelial proliferation of axons may be one of the characteristics of mucosal traumatic neuroma.

ジャーナルJournal of Cutaneous Pathology
出版ステータス出版済み - 3 2008

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Histology
  • Dermatology

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