Trends in blood pressure control and medication use during 20 years in a hypertension clinic in Japan

Yasuo Kansui, Ai Ibaraki, Kenichi Goto, Yoshie Haga, Takunori Seki, Tomohiro Takiguchi, Toshio Ohtsubo, Takanari Kitazono, Kiyoshi Matsumura

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

抄録

Guidelines for the management of hypertension have recommended strict control of blood pressure to help prevent cardiovascular disease. The aim of the present study was to evaluate the current status of blood pressure control and trends over the past two decades. Four hundred patients treated for hypertension at Kyushu University Hospital were included in the present study. Blood pressure levels and prescribed antihypertensive drugs were examined in 2011. The average blood pressure was 129/ 74 mmHg, and the number of prescribed antihypertensive drugs was 2.2. Angiotensin II receptor antagonists, angiotensin-converting enzyme inhibitors, calcium channel blockers, diuretics, alpha-blockers, and beta-blockers were prescribed in 66%, 5%, 78%, 21%, 12%, and 27% of the cases, respectively. Systolic blood pressure was significantly higher, and diastolic blood pressure was significantly lower in patients aged 80 years or older compared with the younger patients (<80 and ≥80 years, 128/75 mmHg and 133/68 mmHg, respectively). The number of prescribed antihypertensive drugs was similar between the two groups. Sixty-five patients were continuously treated for 20 years. The average blood pressure of these patients significantly decreased from 142/87 mmHg in 1991 to 128/71 mmHg in 2011, accompanied with an increase in the number of antihypertensive drugs from 1.6 in 1991 to 2.7 in 2011. These findings suggest that the revised guidelines for the management of hypertension may have contributed to increased awareness and better management of blood pressure levels.

元の言語英語
ページ(範囲)299-304
ページ数6
ジャーナルClinical and Experimental Hypertension
38
発行部数3
DOI
出版物ステータス出版済み - 4 2 2016

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Japan
Blood Pressure
Hypertension
Antihypertensive Agents
Guidelines
Angiotensin Receptor Antagonists
Population Growth
Calcium Channel Blockers
Angiotensin-Converting Enzyme Inhibitors
Diuretics
Cardiovascular Diseases

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Physiology

これを引用

Trends in blood pressure control and medication use during 20 years in a hypertension clinic in Japan. / Kansui, Yasuo; Ibaraki, Ai; Goto, Kenichi; Haga, Yoshie; Seki, Takunori; Takiguchi, Tomohiro; Ohtsubo, Toshio; Kitazono, Takanari; Matsumura, Kiyoshi.

:: Clinical and Experimental Hypertension, 巻 38, 番号 3, 02.04.2016, p. 299-304.

研究成果: ジャーナルへの寄稿記事

Kansui, Yasuo ; Ibaraki, Ai ; Goto, Kenichi ; Haga, Yoshie ; Seki, Takunori ; Takiguchi, Tomohiro ; Ohtsubo, Toshio ; Kitazono, Takanari ; Matsumura, Kiyoshi. / Trends in blood pressure control and medication use during 20 years in a hypertension clinic in Japan. :: Clinical and Experimental Hypertension. 2016 ; 巻 38, 番号 3. pp. 299-304.
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abstract = "Guidelines for the management of hypertension have recommended strict control of blood pressure to help prevent cardiovascular disease. The aim of the present study was to evaluate the current status of blood pressure control and trends over the past two decades. Four hundred patients treated for hypertension at Kyushu University Hospital were included in the present study. Blood pressure levels and prescribed antihypertensive drugs were examined in 2011. The average blood pressure was 129/ 74 mmHg, and the number of prescribed antihypertensive drugs was 2.2. Angiotensin II receptor antagonists, angiotensin-converting enzyme inhibitors, calcium channel blockers, diuretics, alpha-blockers, and beta-blockers were prescribed in 66{\%}, 5{\%}, 78{\%}, 21{\%}, 12{\%}, and 27{\%} of the cases, respectively. Systolic blood pressure was significantly higher, and diastolic blood pressure was significantly lower in patients aged 80 years or older compared with the younger patients (<80 and ≥80 years, 128/75 mmHg and 133/68 mmHg, respectively). The number of prescribed antihypertensive drugs was similar between the two groups. Sixty-five patients were continuously treated for 20 years. The average blood pressure of these patients significantly decreased from 142/87 mmHg in 1991 to 128/71 mmHg in 2011, accompanied with an increase in the number of antihypertensive drugs from 1.6 in 1991 to 2.7 in 2011. These findings suggest that the revised guidelines for the management of hypertension may have contributed to increased awareness and better management of blood pressure levels.",
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