Troponin isoform dependent pH dependence of the Ca2+-activated myofibrillar atpase activity of avian slow and fast skeletal muscles

Akira Kawashima, Sachio Morimoto, Akito Suzuki, Fumie Shiraishi, Iwao Ohtsuki

研究成果: Contribution to journalArticle査読

5 被引用数 (Scopus)

抄録

The effects of acidic pH were examined on the Ca2+-sensitive ATPase activity of chicken fast and slow skeletal muscle myofibrils. In both types of myofibrils the Ca2+-sensitivity declined on decreasing pH from 7.4 to 6.2, but the slow skeletal muscle myofibrils were found to exhibit a Ca2+-sensitive ATPase activity which was more resistant to acidic pH compared to the fast skeletal muscle myofibrils. The results obtained by using a novel method for replacing whole troponin complex in myofibrils provide the first evidence that troponin is responsible for this higher resistibility of slow skeletal muscle myofibrils to acidosis.

本文言語英語
ページ(範囲)585-592
ページ数8
ジャーナルBiochemical and Biophysical Research Communications
207
2
DOI
出版ステータス出版済み - 1 1 1995

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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