Turnover ability of a designed RNA acting as a template for chemical peptide ligation

Kohei Yamashita, Norimasa Kashiwagi, Hiroyuki Furuta, Yoshiya Ikawa

    研究成果: Contribution to journalArticle査読

    4 被引用数 (Scopus)

    抄録

    A designed self-folding RNA possessing two peptiderecognition motifs served as a template for the chemical ligation of two RNA-binding peptides under stoichiometric conditions. In this study, we investigated theturnover ability of this template RNA in facilitation of peptide ligation and found that the RNA exhibited modest turnover ability under conditions in which its 3D structure was marginally stable.

    本文言語英語
    ページ(範囲)2021-2024
    ページ数4
    ジャーナルBioscience, Biotechnology and Biochemistry
    75
    10
    DOI
    出版ステータス出版済み - 2011

    All Science Journal Classification (ASJC) codes

    • バイオテクノロジー
    • 分析化学
    • 生化学
    • 応用微生物学とバイオテクノロジー
    • 分子生物学
    • 有機化学

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