Two cases of histiocytic necrotizlng lymphadenitis (kikuchi-fujimoto’s disease) following diffuse large B-cell lymphoma

Tadashi Yoshino, Tomohiko Mannami, Koichi Ichimura, Katsuto Takenaka, Soichiro Nose, Ichiro Yamadori, Tadaatsu Akagi

研究成果: Contribution to journalArticle査読

30 被引用数 (Scopus)

抄録

Histiocytic necrotizing lymphadenitis (HNL) is often mistaken for malignant lymphoma clinically and is also sometimes difficult to differentiate from lymphoma even histopathologically. In this report, we describe the first 2 reported cases of HNL following non-Hodgkin’s lymphomas. The patients were 27- and 30-year-old women who developed cervical and axillary lymph node swellings, respectively, in the course of remission of diffuse large B-cell lymphoma. The affected lymph nodes showed the typical histology of HNL: irregular-shaped ’necrotic’ foci with histiocytes engulfing apoptotic bodies intermingled with large-sized blastic lymphocytes. These findings mimicked the partial involvement of large-cell lymphoma. However, the blastic cells were almost exclusively T cells, and numerous apoptotic bodies were present, which excluded the possibility of recurrence of diffuse large B-cell lymphoma. Copyright (C) 2000 by W.B. Saunders Company.

本文言語英語
ページ(範囲)1328-1331
ページ数4
ジャーナルHuman Pathology
31
10
DOI
出版ステータス出版済み - 2000

All Science Journal Classification (ASJC) codes

  • 病理学および法医学

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