Two Cases of Large Filar Cyst Associated with Terminal Lipoma: Relationship with Retained Medullary Cord

Nobutaka Mukae, Takato Morioka, Satoshi O. Suzuki, Nobuya Murakami, Takafumi Shimogawa, Akiko Kanata, Haruhisa Tsukamoto, Masahiro Mizoguchi

研究成果: Contribution to journalArticle査読

4 被引用数 (Scopus)

抄録

Background: A small, incidental filar cyst associated with terminal lipoma is thought to be caused by failure of secondary neurulation; however, the precise embryologic background is not fully understood. Retained medullary cord (RMC) also originates from late arrest of secondary neurulation. The central feature of RMC histopathology is a central canal-like ependyma-lined lumen with surrounding neuroglial core. Case Description: We surgically treated 2 patients with a large cyst in the rostral part of the filum and lipoma in the caudal filum. At cord untethering surgery, the filum was severed at the caudal part of the cyst. Histopathologically, the filar cyst was the cystic dilatation of the central canal-like structure at the marginal part of the lipoma. The central canal-like structure was continuous caudally in the lipoma, and its size decreased toward the caudal side. Conclusions: The present findings support the idea raised by Pang et al that entities such as filar cyst, terminal lipomas, and RMC can all be considered consequences of a continuum of regression failure occurring during late secondary neurulation.

本文言語英語
ページ(範囲)294-298
ページ数5
ジャーナルWorld Neurosurgery
142
DOI
出版ステータス出版済み - 10 2020

All Science Journal Classification (ASJC) codes

  • 外科
  • 臨床神経学

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