Two cytotoxic squalene-derived polyethers from the Japanese red alga Chondria armata

Toshiyuki Hamada, Kazushi Kobayashi, Naomichi Arima, Fumito Tani, Charles Santhanaraju Vairappan, Satoaki Onitsuka, Hiroaki Okamura

研究成果: Contribution to journalArticle査読

抄録

The red alga Chondria armata is known to produce and contain a rich diversity of secondary metabolites, such as domoic acid-related alkaloids and triterpene polyethers. Our investigation on red alga C. armata from Kagoshima coast, Japan, resulted in the isolation of two new triterpene polyethers, bandokorols A (1) and B (2). The structures of these compounds were determined based on spectroscopic data such as infrared (FTIR), 1H-NMR, APT, 1H–1H-COSY, HSQC, HMBC, NOESY and FAB mass spectrometry (HRFABMS). The anticancer potentials of these compounds were tested against adult T-cell leukaemia (ATL), S1T cells and their IC50 values are reported here.

本文言語英語
ページ(範囲)5075-5080
ページ数6
ジャーナルNatural Product Research
35
23
DOI
出版ステータス出版済み - 2021

All Science Journal Classification (ASJC) codes

  • 分析化学
  • 生化学
  • 植物科学
  • 有機化学

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