Two new biologically active triterpene saponins from Acanthophyllum squarrosum

Ghezala Gaidi, Tomofumi Miyamoto, Abdolhossein Rustaiyan, Véronique Laurens, Marie Aleth Lacaille-Dubois

研究成果: Contribution to journalArticle査読

29 被引用数 (Scopus)

抄録

Two novel triterpenoid saponins (1 and 2) have been isolated from the roots of Acanthophyllum squarrosum. The structures were established mainly by a combination of 2D NMR techniques as 3-O-β-D-galactopyranosyl-(1→2)[β-D-xylopyranosyl-(1→3)-β-D-glucuronopyra nosylgypsogenin-28-O-β-D-xylopyranosyl-(1→3)-β-D-xylopyranosyl-(1→4)-α-L -rhamnopyranosyl-(1→4)-[α-L-rhamnopyranosyl-(1→3)]-β-D-fucopyranoside (1) and 3-O-β-D-glucopyranosylgypsogenin-28-O-α-L-rhamnopyranosyl-(1→2)-α-L-arabi nopyranosyl-(1→2)-[β-D-glucopyranosyl-(1→6)]-β-D-glucopyranoside (2). Compound 1 showed a moderate concentration-dependent immunomodulatory effect in an in vitro lymphocyte proliferation assay.

本文言語英語
ページ(範囲)1497-1502
ページ数6
ジャーナルJournal of Natural Products
63
11
DOI
出版ステータス出版済み - 12 10 2000

All Science Journal Classification (ASJC) codes

  • 分析化学
  • 分子医療
  • 薬理学
  • 薬科学
  • 創薬
  • 補完代替医療
  • 有機化学

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