Two new biologically active triterpene saponins from Acanthophyllum squarrosum

Ghezala Gaidi, Tomofumi Miyamoto, Abdolhossein Rustaiyan, Véronique Laurens, Marie Aleth Lacaille-Dubois

研究成果: ジャーナルへの寄稿記事

26 引用 (Scopus)

抄録

Two novel triterpenoid saponins (1 and 2) have been isolated from the roots of Acanthophyllum squarrosum. The structures were established mainly by a combination of 2D NMR techniques as 3-O-β-D-galactopyranosyl-(1→2)[β-D-xylopyranosyl-(1→3)-β-D-glucuronopyra nosylgypsogenin-28-O-β-D-xylopyranosyl-(1→3)-β-D-xylopyranosyl-(1→4)-α-L -rhamnopyranosyl-(1→4)-[α-L-rhamnopyranosyl-(1→3)]-β-D-fucopyranoside (1) and 3-O-β-D-glucopyranosylgypsogenin-28-O-α-L-rhamnopyranosyl-(1→2)-α-L-arabi nopyranosyl-(1→2)-[β-D-glucopyranosyl-(1→6)]-β-D-glucopyranoside (2). Compound 1 showed a moderate concentration-dependent immunomodulatory effect in an in vitro lymphocyte proliferation assay.

元の言語英語
ページ(範囲)1497-1502
ページ数6
ジャーナルJournal of Natural Products
63
発行部数11
DOI
出版物ステータス出版済み - 12 10 2000

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Triterpenes
Lymphocytes
Saponins
Assays
Nuclear magnetic resonance
In Vitro Techniques

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

これを引用

Two new biologically active triterpene saponins from Acanthophyllum squarrosum. / Gaidi, Ghezala; Miyamoto, Tomofumi; Rustaiyan, Abdolhossein; Laurens, Véronique; Lacaille-Dubois, Marie Aleth.

:: Journal of Natural Products, 巻 63, 番号 11, 10.12.2000, p. 1497-1502.

研究成果: ジャーナルへの寄稿記事

Gaidi, G, Miyamoto, T, Rustaiyan, A, Laurens, V & Lacaille-Dubois, MA 2000, 'Two new biologically active triterpene saponins from Acanthophyllum squarrosum', Journal of Natural Products, 巻. 63, 番号 11, pp. 1497-1502. https://doi.org/10.1021/np000212+
Gaidi, Ghezala ; Miyamoto, Tomofumi ; Rustaiyan, Abdolhossein ; Laurens, Véronique ; Lacaille-Dubois, Marie Aleth. / Two new biologically active triterpene saponins from Acanthophyllum squarrosum. :: Journal of Natural Products. 2000 ; 巻 63, 番号 11. pp. 1497-1502.
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