Tyrosinase inhibitory effect of quercetin 4'-O -β- D-glucopyranoside from dried skin of red onion (Allium cepa)

Enos Tangke Arung, Irawan Wijaya Kusuma, Kuniyoshi Shimizu, Ryuichiro Kondo

研究成果: Contribution to journalArticle

11 引用 (Scopus)

抜粋

In an effort to find a new whitening agent, we focused our attention on Allium cepa (red onion). Based on biologically guided fractionation using mushroom tyrosinase, quercetin 4'-O -βD-glucopyranoside was isolated from the dried skin of A. cepa. Quercetin 4'-O - βD-glucopyranoside showed tyrosinase inhibitory activity using L-tyrosine or L-DOPA as a substrate, with IC50 values of 4.3 and 52.7μ M, respectively. Based on the results obtained, the dried skin of red onion possesses ingredients with potential for skin-whitening cosmetics with anti-tyrosinase activity.

元の言語英語
ページ(範囲)256-263
ページ数8
ジャーナルNatural Product Research
25
発行部数3
DOI
出版物ステータス出版済み - 2 2011

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Plant Science
  • Organic Chemistry

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