Tyrosinase inhibitory effect of quercetin 4'-O -β- D-glucopyranoside from dried skin of red onion (Allium cepa)

Enos Tangke Arung, Irawan Wijaya Kusuma, Kuniyoshi Shimizu, Ryuichiro Kondo

研究成果: Contribution to journalArticle査読

12 被引用数 (Scopus)

抄録

In an effort to find a new whitening agent, we focused our attention on Allium cepa (red onion). Based on biologically guided fractionation using mushroom tyrosinase, quercetin 4'-O -βD-glucopyranoside was isolated from the dried skin of A. cepa. Quercetin 4'-O - βD-glucopyranoside showed tyrosinase inhibitory activity using L-tyrosine or L-DOPA as a substrate, with IC50 values of 4.3 and 52.7μ M, respectively. Based on the results obtained, the dried skin of red onion possesses ingredients with potential for skin-whitening cosmetics with anti-tyrosinase activity.

本文言語英語
ページ(範囲)256-263
ページ数8
ジャーナルNatural Product Research
25
3
DOI
出版ステータス出版済み - 2 2011

All Science Journal Classification (ASJC) codes

  • 分析化学
  • 生化学
  • 植物科学
  • 有機化学

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