Unsymmetric indolylmaleimides: Synthesis, photophysical properties and amyloid detection

Manabu Nakazono, Konen Obayashi, Yuji Oshikawa, Kazushi Tani, Genki Suenaga, Yukio Ando, Shinkoh Nanbu, Ryoichi Kuwano

研究成果: ジャーナルへの寄稿記事

4 引用 (Scopus)

抄録

Various unsymmetric indolylmaleimides were synthesized. Their photophysical properties and affinities for amyloid fibrils were evaluated. Some unsymmetric indolylmaleimides have large Stokes shifts of more than 120 nm, fluorescence emission maxima wavelengths of more than 550 nm and different emissions under UV irradiation at 365 nm. From the results of histopathologic methods using stains, 3-(1H-indol-3-yl)-1-methyl-4-phenyl-1H-pyrrole-2,5-dione has high selectivity for amyloid fibrils in senile systemic amyloidosis.

元の言語英語
ページ(範囲)39-46
ページ数8
ジャーナルJournal of Photochemistry and Photobiology A: Chemistry
289
DOI
出版物ステータス出版済み - 9 1 2014

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Amyloid
Pyrroles
Dione
pyrroles
synthesis
affinity
Coloring Agents
selectivity
Fluorescence
Irradiation
Wavelength
fluorescence
irradiation
shift
wavelengths

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Chemical Engineering(all)
  • Physics and Astronomy(all)

これを引用

Unsymmetric indolylmaleimides : Synthesis, photophysical properties and amyloid detection. / Nakazono, Manabu; Obayashi, Konen; Oshikawa, Yuji; Tani, Kazushi; Suenaga, Genki; Ando, Yukio; Nanbu, Shinkoh; Kuwano, Ryoichi.

:: Journal of Photochemistry and Photobiology A: Chemistry, 巻 289, 01.09.2014, p. 39-46.

研究成果: ジャーナルへの寄稿記事

Nakazono, Manabu ; Obayashi, Konen ; Oshikawa, Yuji ; Tani, Kazushi ; Suenaga, Genki ; Ando, Yukio ; Nanbu, Shinkoh ; Kuwano, Ryoichi. / Unsymmetric indolylmaleimides : Synthesis, photophysical properties and amyloid detection. :: Journal of Photochemistry and Photobiology A: Chemistry. 2014 ; 巻 289. pp. 39-46.
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AU - Nanbu, Shinkoh

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