Upregulation of cytochrome p450s following exposure of the silkmoth, Bombyx mori to insecticides

研究成果: ジャーナルへの寄稿記事

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We examined which proteins were enhanced in the silkmoth in response to its exposure to insecticides. We previously found that the levels of four cytochrome P450s (CYPs) were higher following insecticide exposure (Yamamoto et al., 2010). In this study, we focused on other mRNAs encoding the silkmoth CYP proteins (CYP6B29, CYP18A1, CYP366A1, CYP302A1) induced. mRNA expression analysis revealed that each CYP mRNA was expressed in a tissue-specifc manner and that expression was developmentally regulated. Quantitative PCR revealed that these CYP mRNAs were upregulated in the larval fat body after exposure of the silkmoth to various insecticides. Our results suggest that the CYPs can contribute to insecticide resistance in Lepidopterans.

元の言語英語
ページ(範囲)33-38
ページ数6
ジャーナルJournal of Insect Biotechnology and Sericology
82
発行部数2
DOI
出版物ステータス出版済み - 12 12 2013

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All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Applied Microbiology and Biotechnology
  • Business, Management and Accounting(all)
  • Agricultural and Biological Sciences(all)
  • Insect Science
  • Industrial and Manufacturing Engineering

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