Urea-accelerated iridium-catalyzed 2-position-selective CH borylation of indole derivatives

研究成果: Contribution to journalArticle査読

抄録

We developed iridium-catalyzed 2-position-selective CH borylation of indole derivatives by modifying the structure of a bipyridine-type ligand. The yields ranged from good to excellent, even on a gram scale, and were dramatically improved by the addition of a urea derivative catalyst. The introduced boryl group was converted to chloro, bromo, and phenyl groups without isolation of the borylated intermediate. Preliminary results indicated the importance of hydrogen bonding between the substrate and the urea additive.

本文言語英語
ページ(範囲)808-811
ページ数4
ジャーナルChemistry Letters
50
4
DOI
出版ステータス出版済み - 4 2021

All Science Journal Classification (ASJC) codes

  • 化学 (全般)

フィンガープリント

「Urea-accelerated iridium-catalyzed 2-position-selective CH borylation of indole derivatives」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル