Use of acetate as a leaving group in palladium-catalyzed nucleophilic substitution of benzylic esters

Masashi Yokogi, Ryoichi Kuwano

研究成果: Contribution to journalArticle査読

32 被引用数 (Scopus)

抄録

The palladium complex prepared in situ from [Pd(η3-C3H5)(cod)]BF4 and bidentate phosphine DPPF was a good catalyst for the nucleophilic substitution of benzyl acetate. Significant acceleration of the palladium-catalyzed substitution was observed when an alcohol was employed as a reaction solvent. The palladium catalyst was effective for the benzylation of various stabilized carbanions, amines, and benzenesulfinate with benzylic acetates.

本文言語英語
ページ(範囲)6109-6112
ページ数4
ジャーナルTetrahedron Letters
48
35
DOI
出版ステータス出版済み - 8 27 2007

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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