Vascular remodeling and angiotensin II

M. Takemoto, Kensuke Egashira

研究成果: ジャーナルへの寄稿評論記事

2 引用 (Scopus)

抄録

Numerous pharmacological approaches have failed to modify the high incidence of restenosis after balloon coronary angioplasty. This inability to alter the restenosis process was caused in part by our incomplete understanding of its pathology. Neointimal formation and geometric remodeling cause the restenosis after angioplasty. The development of restenosis involves vascular smooth muscle cells (VSMCs) migration and proliferation. Angiotensin II has been shown to stimulate the growth of VSMCs via an action on the angiotensin II AT1 receptor subtype. Angiotensin II AT1 receptor antagonists can block the angiotensin II-induced these actions. Angiotensin II AT1 receptor antagonists may block the restenosis after balloon coronary angioplasty.

元の言語英語
ページ(範囲)1158-1163
ページ数6
ジャーナルNippon rinsho. Japanese journal of clinical medicine
57
発行部数5
出版物ステータス出版済み - 1 1 1999

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Angiotensin Type 1 Receptor
Angiotensin II
Coronary Balloon Angioplasty
Angiotensin Receptor Antagonists
Vascular Smooth Muscle
Smooth Muscle Myocytes
Angiotensin Receptors
Angioplasty
Cell Movement
Cell Proliferation
Pharmacology
Pathology
Incidence
Growth
Vascular Remodeling

All Science Journal Classification (ASJC) codes

  • Medicine(all)

これを引用

Vascular remodeling and angiotensin II. / Takemoto, M.; Egashira, Kensuke.

:: Nippon rinsho. Japanese journal of clinical medicine, 巻 57, 番号 5, 01.01.1999, p. 1158-1163.

研究成果: ジャーナルへの寄稿評論記事

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