Vascular remodeling and angiotensin II

M. Takemoto, K. Egashira

研究成果: Contribution to journalReview article

2 引用 (Scopus)

抜粋

Numerous pharmacological approaches have failed to modify the high incidence of restenosis after balloon coronary angioplasty. This inability to alter the restenosis process was caused in part by our incomplete understanding of its pathology. Neointimal formation and geometric remodeling cause the restenosis after angioplasty. The development of restenosis involves vascular smooth muscle cells (VSMCs) migration and proliferation. Angiotensin II has been shown to stimulate the growth of VSMCs via an action on the angiotensin II AT1 receptor subtype. Angiotensin II AT1 receptor antagonists can block the angiotensin II-induced these actions. Angiotensin II AT1 receptor antagonists may block the restenosis after balloon coronary angioplasty.

元の言語英語
ページ(範囲)1158-1163
ページ数6
ジャーナルNippon rinsho. Japanese journal of clinical medicine
57
発行部数5
出版物ステータス出版済み - 5 1999

All Science Journal Classification (ASJC) codes

  • Medicine(all)

フィンガープリント Vascular remodeling and angiotensin II' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

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