Vba2p, A vacuolar membrane protein involved in basic amino acid transport in schizosaccharomyces pombe

Naoko Sugimoto, Tomoko Iwaki, Soracom Chardwiriyapreecha, Masamitsu Shimazu, Takayuki Sekito, Kaoru Takegawa, Yoshimi Kakinuma

研究成果: ジャーナルへの寄稿記事

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A recent study filling the gap in the genome sequence in the left arm of chromosome 2 of Schizosaccharomyces pombe revealed a homolog of budding yeast Vba2p, a vacuolar transporter of basic amino acids. GFP-tagged Vba2p in fission yeast was localized to the vacuolar membrane. Upon disruption of vba2, the uptake of several amino acids, including lysine, histidine, and arginine, was impaired. A transient increase in lysine uptake under nitrogen starvation was lowered by this mutation. These findings suggest that Vba2p is involved in basic amino acid transport in S. pombe under diverse conditions.

元の言語英語
ページ(範囲)2166-2169
ページ数4
ジャーナルBioscience, Biotechnology and Biochemistry
74
発行部数10
DOI
出版物ステータス出版済み - 11 8 2010

    フィンガープリント

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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