Ventral abdominal wall dysmorphogenesis of Msx1/Msx2 double-mutant mice

Hidenao Ogi, Kentaro Suzuki, Yukiko Ogino, Mika Kamimura, Mami Miyado, Xu Ying, Zunyi Zhang, Masanori Shinohara, Yiping Chen, Gen Yamada

研究成果: ジャーナルへの寄稿記事

26 引用 (Scopus)

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Msx1 and Msx2 genes encode the homeodomain transcription factors. Several gene knockout mice and expression studies suggest that they possess functionally redundant roles in embryogenesis. In this study, we revealed that Msx1 and Msx2 were expressed during ventral body wall formation in an overlapping manner. Msx1/Msx2 double-mutant mice displayed embryonic abdominal wall defects with disorganized muscle layers and connective tissues. These findings indicate that Msx1 and Msx2 play roles in concert during embryonic ventral abdominal wall formation.

元の言語英語
ページ(範囲)424-430
ページ数7
ジャーナルAnatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology
284
発行部数1
DOI
出版物ステータス出版済み - 5 1 2005
外部発表Yes

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All Science Journal Classification (ASJC) codes

  • Anatomy
  • Agricultural and Biological Sciences (miscellaneous)

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