Ventricular energetics in endoventricular circular patch plasty for dyskinetic anterior left ventricular aneurysm

Yoshihisa Tanoue, Hiromi Ando, Fumio Fukumura, Masayoshi Umesue, Takayuki Uchida, Kenichiro Taniguchi, Jiro Tanaka

研究成果: ジャーナルへの寄稿学術誌査読

18 被引用数 (Scopus)

抄録

Background. The endoventricular circular patch plasty (Dor procedure) applies to patients with a left ventricular dysfunction due to an ischemic dilated ventricle. In the present study, we analyzed left ventricular energetics in patients who underwent the Dor procedure. Methods. We measured left ventricular contractility (end-systolic elastance; Ees), afterload (effective arterial elastance; Ea), and efficiency (ventriculoarterial coupling; Ea/Ees, and the ratio of stroke work and pressure-volume area; SW/PVA) based on the cardiac catheterization data before and after the Dor procedure in 8 patients with a postinfarction dyskinetic anterior left ventricular aneurysm. Concomitant procedures included coronary artery bypass grafting in all patients, mitral valve repair in one patient, and cryoablation in one patient. End-systolic elastance (Ees) and Ea were approximated as follows: Ees = mean arterial pressure/minimal left ventricular volume, and Ea = maximal left ventricular pressure/(maximal left ventricular volume-minimal left ventricular volume), and thereafter Ea/Ees and SW/PVA were calculated. The left ventricular volume was normalized with the body surface area. Results. End-systolic elastance (Ees) increased after the Dor procedure (from 1.15 ± 0.60 to 1.86 ± 0.84 mm Hg·m2·mL-1, p < 0.01), thus resulting in an improvement in Ea/Ees and SW/PVA (from 2.94 ± 1.11 to 1.64 ± 0.49, p < 0.01, and from 0.426 ± 0.110 to 0.559 ± 0.082, p < 0.01, respectively), even though Ea did not substantially change (from 2.96 ± 0.78 to 2.74 ± 0.55 mm Hg·m2·mL-1, p = 0.4). Conclusions. Left ventricular contractility and efficiency improves after the Dor procedure in patients with a dyskinetic anterior left ventricular aneurysm. However, afterload does not change. The use of appropriate afterload-reducing therapy thus plays an especially important role in the management of patients who undergo the Dor procedure.

本文言語英語
ページ(範囲)1205-1208
ページ数4
ジャーナルAnnals of Thoracic Surgery
75
4
DOI
出版ステータス出版済み - 4月 1 2003
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 外科
  • 呼吸器内科
  • 循環器および心血管医学

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