Vitellogenin receptor mutation leads to the oogenesis mutant phenotype "scanty vitellin" of the silkworm, bombyx mori

Ying Lin, Yan Meng, Yan Xia Wang, Juan Luo, Susumu Katsuma, Cong Wen Yang, Yutaka Banno, Takahiro Kusakabe, Toru Shimada, Qing You Xia

研究成果: Contribution to journalArticle査読

52 被引用数 (Scopus)

抄録

Background: The vitellogenin receptor (VgR) mediates the uptake of vitellogenin (Vg) from the hemolymph by developing oocytes. Results: VgR with the mutational EGF1 domain can bind ligand proteins but cannot be dissociated under acidic conditions. The mutant is lethal in embryos. Conclusion: Bombyx mori VgR (BmVgR) has an important role in egg formation and embryonic development. Significance: BmVgR is a potential target for pest control.

本文言語英語
ページ(範囲)13345-13355
ページ数11
ジャーナルJournal of Biological Chemistry
288
19
DOI
出版ステータス出版済み - 5 10 2013

All Science Journal Classification (ASJC) codes

  • 生化学
  • 分子生物学
  • 細胞生物学

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