抄録
Background: The vitellogenin receptor (VgR) mediates the uptake of vitellogenin (Vg) from the hemolymph by developing oocytes. Results: VgR with the mutational EGF1 domain can bind ligand proteins but cannot be dissociated under acidic conditions. The mutant is lethal in embryos. Conclusion: Bombyx mori VgR (BmVgR) has an important role in egg formation and embryonic development. Significance: BmVgR is a potential target for pest control.
本文言語 | 英語 |
---|---|
ページ(範囲) | 13345-13355 |
ページ数 | 11 |
ジャーナル | Journal of Biological Chemistry |
巻 | 288 |
号 | 19 |
DOI | |
出版ステータス | 出版済み - 5月 10 2013 |
!!!All Science Journal Classification (ASJC) codes
- 生化学
- 分子生物学
- 細胞生物学