Wash-free detection of biomaterial utilizing magnetic markers and MR sensor

Kohta Irie, Kazuki Akiyoshi, Takashi Yoshida, Keiji Enpuku

研究成果: ジャーナルへの寄稿記事

抄録

We have been developing a wash-free detection of biological targets using magnetic markers and magneto-resistive (MR) sensor. In this method, bound and unbound markers can be magnetically distinguished by using the Brownian relaxation. Thus, conventional time-consuming washing process to separate them can be eliminated. Using the magnetic method, we demonstrated the detection of C-reactive protein (CRP). CRPs with concentration from 0.1 ng/mL to 100 ng/mL were successfully detected, which indicates the usefulness of the present method. Reliability of detection was also studied by conducting 10 times experiment. It was shown that the reliability is high when CRP concentration is higher than 3.0 ng/mL. However, it is necessary to improve the reliability for the case of lower concentrations. A method to improve the reliability at lower concentrations was also discussed.

元の言語英語
ページ(範囲)17-22
ページ数6
ジャーナルResearch Reports on Information Science and Electrical Engineering of Kyushu University
24
発行部数1
出版物ステータス出版済み - 1 25 2019

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Biomaterials
Sensors
Proteins
Washing
Experiments

All Science Journal Classification (ASJC) codes

  • Computer Science(all)
  • Electrical and Electronic Engineering

これを引用

Wash-free detection of biomaterial utilizing magnetic markers and MR sensor. / Irie, Kohta; Akiyoshi, Kazuki; Yoshida, Takashi; Enpuku, Keiji.

:: Research Reports on Information Science and Electrical Engineering of Kyushu University, 巻 24, 番号 1, 25.01.2019, p. 17-22.

研究成果: ジャーナルへの寄稿記事

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