Wash-free detection of C-reactive protein based on third-harmonic signal measurement of magnetic markers

Keiji Enpuku, Misako Shibakura, Yujiro Arao, Takako Mizoguchi, Akihiko Kandori, Misato Hara, Keiji Tsukada

研究成果: ジャーナルへの寄稿学術誌査読

10 被引用数 (Scopus)

抄録

We demonstrate wash-free detection of C-reactive proteins (CRPs) based on third-harmonic signal measurement of magnetic markers. In the method presented here, the CRP concentration can be detected from the decrease in the third-harmonic signal from the sample solution. The relationship between the detected signal and the CRP concentration can be modeled quantitatively using a logistic function. The quantities of CRP that were detected using the proposed method showed good correlation with those obtained using the conventional optical method with a washing process. We also demonstrate CRP detection in a hemolysis sample solution that is not optically transparent.

本文言語英語
論文番号090309
ジャーナルJapanese journal of applied physics
57
9
DOI
出版ステータス出版済み - 9月 2018

!!!All Science Journal Classification (ASJC) codes

  • 工学(全般)
  • 物理学および天文学(全般)

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