@article{50cb5592e0554e7d9d9fdf68395be1da,
title = "What determines the specificity and outcomes of Ubiquitin signaling?",
abstract = "Ubiquitin signals and ubiquitin-binding domains are implicated in almost every cellular process, but how is their functionality achieved in cells? We assess recent advances in monitoring the dynamics and specificity of ubiquitin networks in vivo and discuss challenges ahead.",
author = "Fumiyo Ikeda and Nicola Crosetto and Ivan Dikic",
note = "Funding Information: We are grateful to C. Behrends, A. Ciechanover, K. Rittinger, and S. van Wijk for comments and discussions. Research in the I.D. laboratory is supported by the Deutsche Forschungsgemeinschaft, the Cluster of Excellence “Macromolecular Complexes” of the Goethe University Frankfurt (EXC115), and the European Research Council under the European Union's Seventh Framework Programme (FP7/2007-2013)/ERC grant agreement n° [250241-LineUb].",
year = "2010",
month = nov,
day = "24",
doi = "10.1016/j.cell.2010.10.026",
language = "English",
volume = "143",
pages = "677--681",
journal = "Cell",
issn = "0092-8674",
publisher = "Cell Press",
number = "5",
}